ID   Y277_MYCGE              Reviewed;         970 AA.
AC   Q49409; Q49253;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Uncharacterized protein MG277;
GN   OrderedLocusNames=MG277;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 624-678.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L43967; AAC71499.1; -; Genomic_DNA.
DR   EMBL; U02116; AAD12390.1; -; Genomic_DNA.
DR   PIR; F64230; F64230.
DR   RefSeq; WP_010869403.1; NC_000908.2.
DR   AlphaFoldDB; Q49409; -.
DR   STRING; 243273.MG_277; -.
DR   EnsemblBacteria; AAC71499; AAC71499; MG_277.
DR   KEGG; mge:MG_277; -.
DR   eggNOG; COG0841; Bacteria.
DR   HOGENOM; CLU_304380_0_0_14; -.
DR   OMA; DAMAFND; -.
DR   OrthoDB; 676681at2; -.
DR   BioCyc; MGEN243273:G1GJ2-335-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..970
FT                   /note="Uncharacterized protein MG277"
FT                   /id="PRO_0000210502"
FT   TRANSMEM        11..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        515..535
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        537..557
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        558..578
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        614..634
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        645..665
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        726..746
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        762..782
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        789..809
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        816..836
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        877..897
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        903..923
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          366..387
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        673..678
FT                   /note="SGANWK -> QVQMKA (in Ref. 2; AAD12390)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   970 AA;  108164 MW;  F106CDFCC9BD44FF CRC64;
     MRFKKRFSLD WILKIGTILG LVCLGLFGVI FGSYKLLNDS RLGAVFNGST TTTVYFLNHK
     STNNTSLDPQ QTKPTNGIEN ITNIDSFLDG VEKSYANSLF IQGFSSVNIT KNTNDKTASE
     LDNIDKSWLV NGGLPSVTLT FEQNREQAKT RQRKRQVDAQ VRRNAISSVE HNYQLSLETT
     DGVVLFDSLD NNFINASIRA VVPQNTSVNS ALTFEYKLNK NVVTKESLHT DFLDFINSKN
     LSSSDYNTGN GQASVEGNGK FFKQNANGTS SSGNKTLVLW KDKQGALNYV RNIFNVVEGS
     SDYLTFNERE KSLWEFLHAK GSFASGDNLF LNTDANGASP IKKASDITLK NLYYIYAAPN
     HFSAVASNSN DNNNQNNNNN NNSSDVITVS NSADTRKLRS ADSSGFSGLF HNYIISEIRT
     EDPVSKTGDP VKINPTLQSF LDTNNQRIEY GGNIKFQVGN FLSSDGTYTP PNFVTAATVK
     ELLTNPFPTA ATIATAKTSL VNAPLANTIT DVSNFASSFI AFGIIVLIAA VLLTLRYKLL
     GLYKALALGL SVVSSLVIFS AVGGVVDVFS FVGIFFVIAI NLINLLNLGE LFLRNIRNNA
     SIIESWKLCL KRSFFANLEF HITWLISALV VIYLSNYQVQ QLANLMAISA ITSYFFSYGI
     SIVLISLFVS SESGANWKLF LYQKDAKALT KTSSNYSLLS STSDLNTDFF ITKNQHDFFL
     KNNWKFLFVW LILLAIGVVM LVLYLVQPNL LGEFLAADVE SSNGIIAGIG IVSLLYLAYC
     LIRYGVAYCL SYLVSFILLC SGLFAVMYLT NYLFSIDQST IQLITFVYLF WLFFAAKVSQ
     TTTWTYFYWF KRSLKDKVFI KNLFNDNFNS QWKIDLIESS SLVFIFIIYS GFNFGGIDGN
     FNLVIFYLIA IVGLFDVATA FLPMFCFGLI NGWLSPFNYV HSRLSLKHKK HPFKEIDQIE
     EQLIAGINSF