ID   Y2791_MYCMM             Reviewed;         303 AA.
AC   B2HD96;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUN-2008, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Putative S-adenosyl-L-methionine-dependent methyltransferase MMAR_2791;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MMAR_2791;
OS   Mycobacterium marinum (strain ATCC BAA-535 / M).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=216594;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-535 / M;
RX   PubMed=18403782; DOI=10.1101/gr.075069.107;
RA   Stinear T.P., Seemann T., Harrison P.F., Jenkin G.A., Davies J.K.,
RA   Johnson P.D., Abdellah Z., Arrowsmith C., Chillingworth T., Churcher C.,
RA   Clarke K., Cronin A., Davis P., Goodhead I., Holroyd N., Jagels K.,
RA   Lord A., Moule S., Mungall K., Norbertczak H., Quail M.A.,
RA   Rabbinowitsch E., Walker D., White B., Whitehead S., Small P.L., Brosch R.,
RA   Ramakrishnan L., Fischbach M.A., Parkhill J., Cole S.T.;
RT   "Insights from the complete genome sequence of Mycobacterium marinum on the
RT   evolution of Mycobacterium tuberculosis.";
RL   Genome Res. 18:729-741(2008).
CC   -!- FUNCTION: Exhibits S-adenosyl-L-methionine-dependent methyltransferase
CC       activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0677 family. {ECO:0000305}.
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DR   EMBL; CP000854; ACC41233.1; -; Genomic_DNA.
DR   RefSeq; WP_012394497.1; NC_010612.1.
DR   AlphaFoldDB; B2HD96; -.
DR   SMR; B2HD96; -.
DR   STRING; 216594.MMAR_2791; -.
DR   EnsemblBacteria; ACC41233; ACC41233; MMAR_2791.
DR   GeneID; 64261503; -.
DR   KEGG; mmi:MMAR_2791; -.
DR   eggNOG; COG3315; Bacteria.
DR   HOGENOM; CLU_056160_2_1_11; -.
DR   OMA; GSAASMW; -.
DR   OrthoDB; 847145at2; -.
DR   Proteomes; UP000001190; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR011610; CHP00027_methylltransferase.
DR   InterPro; IPR007213; Ppm1/Ppm2/Tcmp.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF04072; LCM; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
DR   TIGRFAMs; TIGR00027; mthyl_TIGR00027; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..303
FT                   /note="Putative S-adenosyl-L-methionine-dependent
FT                   methyltransferase MMAR_2791"
FT                   /id="PRO_0000361166"
FT   BINDING         129
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         158..159
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   303 AA;  33008 MW;  7CB4D3C6E767E6A3 CRC64;
     MTTSEYGSRR SDDDQWDIVS GVGYTALLVA GWRALDTVGP QPLAPDEYAK YFIAASGDAY
     LNDQLAHPPT SVDETAFPRL YGVQTRFFDD FFRSAAAAGT KQAVIVAAGL DSRAYRLEWP
     SGTTVFEIDL PQVLEFKARV LQRHGVEPKA RRNEVAADLR TDWPATLHAA GFEPGQPSAW
     SVEGLLPYLT ADAQDALFAR IDDLCAPGSR IATGALGSRL DHDQLVALEQ THPGVNLSGD
     VNFSALTYDD KTNPAQWLAA RGWVVEPVRN TLELEAGYGM TPPAVDVRLD AIMHSEYIVA
     TKP