ID   Y280_MYCGE              Reviewed;         265 AA.
AC   P47522;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein MG280;
GN   OrderedLocusNames=MG280;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   SEQUENCE REVISION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=16407165; DOI=10.1073/pnas.0510013103;
RA   Glass J.I., Assad-Garcia N., Alperovich N., Yooseph S., Lewis M.R.,
RA   Maruf M., Hutchison C.A. III, Smith H.O., Venter J.C.;
RT   "Essential genes of a minimal bacterium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:425-430(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Not essential, it can be deleted.
CC       {ECO:0000269|PubMed:16407165}.
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DR   EMBL; L43967; AAC71502.2; -; Genomic_DNA.
DR   PIR; I64230; I64230.
DR   RefSeq; WP_009885910.1; NZ_AAGX01000009.1.
DR   AlphaFoldDB; P47522; -.
DR   SMR; P47522; -.
DR   STRING; 243273.MG_280; -.
DR   EnsemblBacteria; AAC71502; AAC71502; MG_280.
DR   KEGG; mge:MG_280; -.
DR   HOGENOM; CLU_1048959_0_0_14; -.
DR   OMA; ACKIYPE; -.
DR   OrthoDB; 2163381at2; -.
DR   BioCyc; MGEN243273:G1GJ2-338-MON; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR030940; MG279/MG280.
DR   TIGRFAMs; TIGR04527; mycoplas_twoTM; 1.
PE   4: Predicted;
KW   Cell membrane; Coiled coil; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..265
FT                   /note="Uncharacterized protein MG280"
FT                   /id="PRO_0000210506"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          131..151
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          72..141
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   265 AA;  29566 MW;  BB2BA19548B4C71D CRC64;
     MVIFINRFSK TILLFFGMLV FVFLLGFGIT ALYFRSTAAN LYVQARNSID SSFNSAKAFA
     NALANSANQF SKSSITNNLD QVKKDLEQSL QKVDEYKKNL ESQNNLGNIS QEKIRELDAT
     KKDLENSKTQ LDNFKNNLDK NGTASSSPSV KKQATADGVI SAVSEFSTQA QSIVSSYEKI
     KNNIPSSEQF NNYYDVTMIT IVAVSGGMLA ILITTIVFSF LTSKKRGLIR FSRFISTEQL
     ADHVNDILDR YPDLEEEVIT ALDHD