ID   Y285_STRP1              Reviewed;         256 AA.
AC   Q9A1G5; Q490V7;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 142.
DE   RecName: Full=Probable ABC transporter ATP-binding protein SPy_0285/M5005_Spy0242;
GN   OrderedLocusNames=SPy_0285, M5005_Spy0242;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Ycf16 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE004092; AAK33355.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ50861.1; -; Genomic_DNA.
DR   RefSeq; NP_268634.1; NC_002737.2.
DR   AlphaFoldDB; Q9A1G5; -.
DR   SMR; Q9A1G5; -.
DR   STRING; 1314.HKU360_00281; -.
DR   PaxDb; Q9A1G5; -.
DR   EnsemblBacteria; AAK33355; AAK33355; SPy_0285.
DR   KEGG; spy:SPy_0285; -.
DR   KEGG; spz:M5005_Spy0242; -.
DR   PATRIC; fig|160490.10.peg.250; -.
DR   HOGENOM; CLU_000604_48_1_9; -.
DR   OMA; MAMLEPK; -.
DR   Proteomes; UP000000750; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProt.
DR   CDD; cd03217; ABC_FeS_Assembly; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR010230; FeS-cluster_ATPase_SufC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR43204; PTHR43204; 1.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR01978; sufC; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell membrane; Membrane; Nucleotide-binding;
KW   Reference proteome; Transport.
FT   CHAIN           1..256
FT                   /note="Probable ABC transporter ATP-binding protein
FT                   SPy_0285/M5005_Spy0242"
FT                   /id="PRO_0000093212"
FT   DOMAIN          4..246
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         36..43
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   256 AA;  28110 MW;  0BE63689F9B4962B CRC64;
     MSILEINNLH VSIEGKEILK GVNLTLKTGE VAAIMGPNGT GKSTLSAAIM GNPNYEVTQG
     QILLDGVNIL DLEVDERARL GLFLAMQYPS EIPGITNAEF MRAAMNAGKA DEDKISVRDF
     ITKLDEKMAL LGMKEEMAER YLNEGFSGGE KKRNEILQLL MLEPKFALLD EIDSGLDIDA
     LKVVSKGVNE MRGKDFGAMI ITHYQRLLNY ITPDLVHVMM DGRIVLSGDA ALATRLEKEG
     YAGIAQDLGI EYKEES