ID   Y2886_MYCTU             Reviewed;         295 AA.
AC   P9WL35; L0TDN5; P65045; Q10831;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Uncharacterized protein Rv2886c;
GN   OrderedLocusNames=Rv2886c; ORFNames=MTCY274.17c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR   EMBL; AL123456; CCP45688.1; -; Genomic_DNA.
DR   PIR; A70925; A70925.
DR   RefSeq; NP_217402.1; NC_000962.3.
DR   RefSeq; WP_003899526.1; NC_000962.3.
DR   AlphaFoldDB; P9WL35; -.
DR   SMR; P9WL35; -.
DR   STRING; 83332.Rv2886c; -.
DR   PaxDb; P9WL35; -.
DR   DNASU; 887424; -.
DR   GeneID; 887424; -.
DR   KEGG; mtu:Rv2886c; -.
DR   PATRIC; fig|83332.111.peg.3212; -.
DR   TubercuList; Rv2886c; -.
DR   eggNOG; COG2452; Bacteria.
DR   OMA; LTYVPGR; -.
DR   PhylomeDB; P9WL35; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005829; C:cytosol; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0000150; F:DNA strand exchange activity; IEA:InterPro.
DR   Gene3D; 3.40.50.1390; -; 1.
DR   InterPro; IPR006119; Resolv_N.
DR   InterPro; IPR036162; Resolvase-like_N_sf.
DR   Pfam; PF00239; Resolvase; 1.
DR   SMART; SM00857; Resolvase; 1.
DR   SUPFAM; SSF53041; SSF53041; 1.
DR   PROSITE; PS51736; RECOMBINASES_3; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..295
FT                   /note="Uncharacterized protein Rv2886c"
FT                   /id="PRO_0000104091"
FT   DOMAIN          151..290
FT                   /note="Resolvase/invertase-type recombinase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
FT   ACT_SITE        159
FT                   /note="O-(5'-phospho-DNA)-serine intermediate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01072"
SQ   SEQUENCE   295 AA;  31860 MW;  4AF4CFBA667CD04E CRC64;
     MSRILTHVPG RTVNRSYALP ALVGSAAGRL SGNHSHGREA YIALPQWACS RQPSTPPLQT
     PGRINALWSL RPVLPMPGRG CQLLRLGGRW LSVVCCRNGS MNLVVWAEGN GVARVIAYRW
     LRVGRLPVPA RRVGRVILVD EPAGQPGRWG RTAVCARLSS ADQKVDLDRQ VVGVTAWATA
     EQIPVGKVVT EVGSALYGRR RTFLTLLGDP TVRRIVMKRR DRLGRFGFEC VQAVLAADGR
     ELVVVDSADV DDDVVGDITE ILTSICARLY GKRAAGNRAA RAVAAAARAG GHEAR