ID   Y2895_MYCTU             Reviewed;         283 AA.
AC   P9WL31; L0TDV8; P65049; Q10816;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Uncharacterized protein Rv2895c;
GN   OrderedLocusNames=Rv2895c; ORFNames=MTCY274.26c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR   EMBL; AL123456; CCP45697.1; -; Genomic_DNA.
DR   PIR; B70926; B70926.
DR   RefSeq; NP_217411.1; NC_000962.3.
DR   RefSeq; WP_003900590.1; NZ_NVQJ01000006.1.
DR   AlphaFoldDB; P9WL31; -.
DR   SMR; P9WL31; -.
DR   STRING; 83332.Rv2895c; -.
DR   TCDB; 3.A.1.21.2; the atp-binding cassette (abc) superfamily.
DR   PaxDb; P9WL31; -.
DR   DNASU; 888180; -.
DR   GeneID; 45426882; -.
DR   GeneID; 888180; -.
DR   KEGG; mtu:Rv2895c; -.
DR   TubercuList; Rv2895c; -.
DR   eggNOG; COG2375; Bacteria.
DR   OMA; TLMGYWR; -.
DR   PhylomeDB; P9WL31; -.
DR   Reactome; R-HSA-1222449; Mtb iron assimilation by chelation.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IDA:MTBBASE.
DR   GO; GO:0071949; F:FAD binding; IBA:GO_Central.
DR   GO; GO:0052851; F:ferric-chelate reductase (NADPH) activity; IBA:GO_Central.
DR   GO; GO:0010106; P:cellular response to iron ion starvation; IEP:MTBBASE.
DR   GO; GO:0033212; P:iron import into cell; IBA:GO_Central.
DR   GO; GO:0015891; P:siderophore transport; IDA:MTBBASE.
DR   Gene3D; 3.40.50.80; -; 1.
DR   InterPro; IPR013113; FAD-bd_9_SIP.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   InterPro; IPR007037; SIP_C.
DR   InterPro; IPR039374; SIP_fam.
DR   PANTHER; PTHR30157; PTHR30157; 1.
DR   Pfam; PF08021; FAD_binding_9; 1.
DR   Pfam; PF04954; SIP; 1.
DR   SUPFAM; SSF63380; SSF63380; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..283
FT                   /note="Uncharacterized protein Rv2895c"
FT                   /id="PRO_0000104093"
FT   DOMAIN          4..131
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00716"
SQ   SEQUENCE   283 AA;  30603 MW;  262B03DE438B8239 CRC64;
     MAGRPLHAFE VVATRHLAPH MVRVVLGGSG FDTFVPSDFT DSYIKLVFVD DDVDVGRLPR
     PLTLDSFADL PTAKRPPVRT MTVRHVDAAA REIAVDIVLH GEHGVAGPWA AGAQRGQPIY
     LMGPGGAYAP DPAADWHLLA GDESAIPAIA AALEALPPDA IGRAFIEVAG PDDEIGLTAP
     DAVEVNWVYR GGRADLVPED RAGDHAPLIE AVTTTAWLPG QVHVFIHGEA QAVMHNLRPY
     VRNERGVDAK WASSISGYWR RGRTEEMFRK WKKELAEAEA GTH