Y2910_MYCTU
ID Y2910_MYCTU Reviewed; 147 AA.
AC P9WL25; L0TDX4; P65053; Q10827;
DT 16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT 16-APR-2014, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Uncharacterized protein Rv2910c;
GN OrderedLocusNames=Rv2910c; ORFNames=MTCY274.42c;
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION AS A DRUG TARGET [LARGE SCALE ANALYSIS].
RX PubMed=19099550; DOI=10.1186/1752-0509-2-109;
RA Raman K., Yeturu K., Chandra N.;
RT "targetTB: a target identification pipeline for Mycobacterium tuberculosis
RT through an interactome, reactome and genome-scale structural analysis.";
RL BMC Syst. Biol. 2:109-109(2008).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- MISCELLANEOUS: Was identified as a high-confidence drug target.
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DR EMBL; AL123456; CCP45712.1; -; Genomic_DNA.
DR PIR; A70928; A70928.
DR RefSeq; NP_217426.1; NC_000962.3.
DR RefSeq; WP_003414734.1; NC_000962.3.
DR AlphaFoldDB; P9WL25; -.
DR SMR; P9WL25; -.
DR STRING; 83332.Rv2910c; -.
DR PaxDb; P9WL25; -.
DR DNASU; 887387; -.
DR GeneID; 887387; -.
DR KEGG; mtu:Rv2910c; -.
DR PATRIC; fig|83332.111.peg.3239; -.
DR TubercuList; Rv2910c; -.
DR eggNOG; COG5517; Bacteria.
DR OMA; NFPAYYH; -.
DR PhylomeDB; P9WL25; -.
DR Proteomes; UP000001584; Chromosome.
DR InterPro; IPR032710; NTF2-like_dom_sf.
DR InterPro; IPR037401; SnoaL-like.
DR Pfam; PF13577; SnoaL_4; 1.
DR SUPFAM; SSF54427; SSF54427; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..147
FT /note="Uncharacterized protein Rv2910c"
FT /id="PRO_0000104098"
SQ SEQUENCE 147 AA; 17049 MW; 4270BF554AAC6808 CRC64;
MCAVLDRSML SVAEISDRLE IQQLLVDYSS AIDQRRFDDL DRVFTPDAYI DYRALGGIDG
RYPKIKQWLS QVLGNFPVYA HMLGNFSVRV DGDTASSRVI CFNPMVFAGD RQQVLFCGLW
YDDDFVRTPD GWRIIRRVET KCFQKMM