ID   Y2912_MYCTO             Reviewed;         195 AA.
AC   P9WMC6; L0TCL6; P67440; Q10829;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 33.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator MT2980;
GN   OrderedLocusNames=MT2980;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
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DR   EMBL; AE000516; AAK47306.1; -; Genomic_DNA.
DR   PIR; C70928; C70928.
DR   RefSeq; WP_003414739.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WMC6; -.
DR   SMR; P9WMC6; -.
DR   EnsemblBacteria; AAK47306; AAK47306; MT2980.
DR   KEGG; mtc:MT2980; -.
DR   PATRIC; fig|83331.31.peg.3220; -.
DR   HOGENOM; CLU_069356_18_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0010468; P:regulation of gene expression; IEA:UniProt.
DR   InterPro; IPR023772; DNA-bd_HTH_TetR-type_CS.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   Pfam; PF00440; TetR_N; 1.
DR   PRINTS; PR00455; HTHTETR.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS01081; HTH_TETR_1; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..195
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   MT2980"
FT                   /id="PRO_0000427327"
FT   DOMAIN          10..70
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
FT   DNA_BIND        33..52
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   195 AA;  21239 MW;  CA62D0761C97EFC1 CRC64;
     MARTQQQRRE ETVARLLQAS IDTIIEVGYA RASAAVITKR AGVSVGALFR HFETMGDFMA
     ATAYEVLRRQ LETFTKQVAE IPADRPALPA ALTILRDITA GSTNAVLYEL MVAARTDEKL
     KETLQNVLGQ YSAKIHDAAR ALPGAESFPE ETFPVIVALM TNVFDGAAIV RGVLPQPELE
     EQRIPMLTAL LTAGL