ID   Y2917_MYCTU             Reviewed;         602 AA.
AC   P9WL21; L0TCM0; Q10966; Q10967;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Uncharacterized protein Rv2917;
GN   OrderedLocusNames=Rv2917; ORFNames=MTCY338.05;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: To M.leprae ML1624. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCP45719.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AL123456; CCP45719.1; ALT_INIT; Genomic_DNA.
DR   PIR; E70747; E70747.
DR   RefSeq; NP_217433.1; NC_000962.3.
DR   AlphaFoldDB; P9WL21; -.
DR   STRING; 83332.Rv2917; -.
DR   PaxDb; P9WL21; -.
DR   PRIDE; P9WL21; -.
DR   DNASU; 887758; -.
DR   GeneID; 887758; -.
DR   KEGG; mtu:Rv2917; -.
DR   PATRIC; fig|83332.12.peg.3251; -.
DR   TubercuList; Rv2917; -.
DR   eggNOG; COG1061; Bacteria.
DR   OMA; HLKKQWA; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR006935; Helicase/UvrB_N.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF04851; ResIII; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..602
FT                   /note="Uncharacterized protein Rv2917"
FT                   /id="PRO_0000104102"
FT   DOMAIN          51..210
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00541"
FT   REGION          430..452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          518..538
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        430..444
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        520..537
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   602 AA;  65825 MW;  321718F78BE746DC CRC64;
     MLHFTAATSR FRLGRERANS VRSDGGWGVL QPVSATFNPP LRGWQRRALV QYLGTQPRDF
     LAVATPGSGK TSFALRIAAE LLRYHTVEQV TVVVPTEHLK VQWAHAAAAH GLSLDPKFAN
     SNPQTSPEYH GVMVTYAQVA SHPTLHRVRT EARKTLVVFD EIHHGGDAKT WGDAIREAFG
     DATRRLALTG TPFRSDDSPI PFVSYQPDAD GVLRSQADHT YGYAEALADG VVRPVVFLAY
     SGQARWRDSA GEEYEARLGE PLSAEQTARA WRTALDPEGE WMPAVITAAD RRLRQLRAHV
     PDAGGMIIAS DRTTARAYAR LLTTMTAEEP TVVLSDDPGS SARITEFAQG TSRWLVAVRM
     VSEGVDVPRL SVGVYATNAS TPLFFAQAIG RFVRSRRPGE TASIFVPSVP NLLQLASALE
     VQRNHVLGRP HRESAHDPLD GDPATRTQTE RGGAERGFTA LGADAELDQV IFDGSSFGTA
     TPTGSDEEAD YLGIPGLLDA EQMRALLHRR QDEQLRKRAQ LQKGATQPAT SGASASVHGQ
     LRDLRRELHT LVSIAHHRTG KPHGWIHDER RRRCGGPPIA AATRAQIKAR IDALRQLNSE
     RS