ID   Y2973_LEPIC             Reviewed;         208 AA.
AC   P61547;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2004, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=UPF0316 protein LIC_12973 {ECO:0000255|HAMAP-Rule:MF_01515};
GN   OrderedLocusNames=LIC_12973;
OS   Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni
OS   (strain Fiocruz L1-130).
OC   Bacteria; Spirochaetes; Leptospirales; Leptospiraceae; Leptospira.
OX   NCBI_TaxID=267671;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Fiocruz L1-130;
RX   PubMed=15028702; DOI=10.1128/jb.186.7.2164-2172.2004;
RA   Nascimento A.L.T.O., Ko A.I., Martins E.A.L., Monteiro-Vitorello C.B.,
RA   Ho P.L., Haake D.A., Verjovski-Almeida S., Hartskeerl R.A., Marques M.V.,
RA   Oliveira M.C., Menck C.F.M., Leite L.C.C., Carrer H., Coutinho L.L.,
RA   Degrave W.M., Dellagostin O.A., El-Dorry H., Ferro E.S., Ferro M.I.T.,
RA   Furlan L.R., Gamberini M., Giglioti E.A., Goes-Neto A., Goldman G.H.,
RA   Goldman M.H.S., Harakava R., Jeronimo S.M.B., Junqueira-de-Azevedo I.L.M.,
RA   Kimura E.T., Kuramae E.E., Lemos E.G.M., Lemos M.V.F., Marino C.L.,
RA   Nunes L.R., de Oliveira R.C., Pereira G.G., Reis M.S., Schriefer A.,
RA   Siqueira W.J., Sommer P., Tsai S.M., Simpson A.J.G., Ferro J.A.,
RA   Camargo L.E.A., Kitajima J.P., Setubal J.C., Van Sluys M.A.;
RT   "Comparative genomics of two Leptospira interrogans serovars reveals novel
RT   insights into physiology and pathogenesis.";
RL   J. Bacteriol. 186:2164-2172(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01515};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01515}.
CC   -!- SIMILARITY: Belongs to the UPF0316 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01515}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAS71523.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE016823; AAS71523.1; ALT_INIT; Genomic_DNA.
DR   AlphaFoldDB; P61547; -.
DR   SMR; P61547; -.
DR   PaxDb; P61547; -.
DR   EnsemblBacteria; AAS71523; AAS71523; LIC_12973.
DR   KEGG; lic:LIC_12973; -.
DR   HOGENOM; CLU_106166_0_0_12; -.
DR   OMA; KLALGYI; -.
DR   Proteomes; UP000007037; Chromosome I.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.70.120; -; 1.
DR   HAMAP; MF_01515; UPF0316; 1.
DR   InterPro; IPR019264; DUF2179.
DR   InterPro; IPR044035; DUF5698.
DR   InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR   InterPro; IPR022930; UPF0316.
DR   PANTHER; PTHR40060; PTHR40060; 1.
DR   Pfam; PF10035; DUF2179; 1.
DR   Pfam; PF18955; DUF5698; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..208
FT                   /note="UPF0316 protein LIC_12973"
FT                   /id="PRO_0000171944"
FT   TRANSMEM        56..76
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01515"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01515"
SQ   SEQUENCE   208 AA;  23481 MW;  8C269BACCF32D400 CRC64;
     MFFQRYLYCM EFSFPLPGNP IFDYVLLPCF IFLSRVTDVS IGTIRVILLT REKKGIAASL
     GFLEVLLWVV VITQVIKNLN NVFCYLAYAG GFATGTFIGM ILEEKLAIGF SLLRIISPQN
     GSEIADKLSE AGYRVTIMNG HGSRGPVKIV FTVLKRKKID QAMKIVQNVE PDVFYSIENA
     RRTNTTTFED SPGLLRRGIL EKILKIRK