ID   Y2994_MYCTO             Reviewed;         445 AA.
AC   P9WJW6; L0TCU9; Q7ARU7; Q8VJ95;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 35.
DE   RecName: Full=Uncharacterized MFS-type transporter MT3072;
GN   OrderedLocusNames=MT3072;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK47401.1; -; Genomic_DNA.
DR   PIR; E70854; E70854.
DR   AlphaFoldDB; P9WJW6; -.
DR   SMR; P9WJW6; -.
DR   EnsemblBacteria; AAK47401; AAK47401; MT3072.
DR   KEGG; mtc:MT3072; -.
DR   HOGENOM; CLU_001265_58_1_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; -; 2.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..445
FT                   /note="Uncharacterized MFS-type transporter MT3072"
FT                   /id="PRO_0000427758"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        243..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        283..303
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        366..386
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          417..445
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   445 AA;  47016 MW;  1E51EAE042F2178B CRC64;
     MSRDPTGVGA RWAIMIVSLG VTASSFLFIN GVAFLIPRLE NARGTPLSHA GLLASMPSWG
     LVVTMFAWGY LLDHVGERMV MAVGSALTAA AAYAAASVHS LLWIGVFLFL GGMAAGGCNS
     AGGRLVSGWF PPQQRGLAMG IRQTAQPLGI ASGALVIPEL AERGVHAGLM FPAVVCTLAA
     VASVLGIVDP PRKSRTKASE QELASPYRGS SILWRIHAAS ALLMMPQTVT VTFMLVWLIN
     HHGWSVAQAG VLVTISQLLG ALGRVAVGRW SDHVGSRMRP VRLIAAAAAA TLFLLAAVDN
     EGSRYDVLLM IAISVIAVLD NGLEAAAITE YAGPYWSGRA LGIQNTTQRL MAAAGPPLFG
     SLITTAAYPT AWALCGVFPL AAVPLVPVRL LPPGLETRAR RQSVRRHRWW QAVRCHAWPN
     GPRRPGPPGQ PRRVRQGGTA ITPPT