ID   Y300_BUCBP              Reviewed;         519 AA.
AC   Q89AI6;
DT   13-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=UPF0053 protein bbp_300;
GN   OrderedLocusNames=bbp_300;
OS   Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=224915;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bp;
RX   PubMed=12522265; DOI=10.1073/pnas.0235981100;
RA   van Ham R.C.H.J., Kamerbeek J., Palacios C., Rausell C., Abascal F.,
RA   Bastolla U., Fernandez J.M., Jimenez L., Postigo M., Silva F.J.,
RA   Tamames J., Viguera E., Latorre A., Valencia A., Moran F., Moya A.;
RT   "Reductive genome evolution in Buchnera aphidicola.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:581-586(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0053 family. {ECO:0000305}.
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DR   EMBL; AE016826; AAO27025.1; -; Genomic_DNA.
DR   RefSeq; WP_011091426.1; NC_004545.1.
DR   AlphaFoldDB; Q89AI6; -.
DR   SMR; Q89AI6; -.
DR   STRING; 224915.bbp_300; -.
DR   EnsemblBacteria; AAO27025; AAO27025; bbp_300.
DR   GeneID; 56470840; -.
DR   KEGG; bab:bbp_300; -.
DR   eggNOG; COG1253; Bacteria.
DR   HOGENOM; CLU_015237_0_0_6; -.
DR   OMA; MRFINRH; -.
DR   OrthoDB; 1917125at2; -.
DR   Proteomes; UP000000601; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR005496; Integral_membrane_TerC.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR005170; Transptr-assoc_dom.
DR   Pfam; PF03471; CorC_HlyC; 1.
DR   Pfam; PF03741; TerC; 1.
DR   SMART; SM01091; CorC_HlyC; 1.
DR   SUPFAM; SSF54631; SSF54631; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51371; CBS; 2.
PE   3: Inferred from homology;
KW   CBS domain; Cell membrane; Membrane; Reference proteome; Repeat;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..519
FT                   /note="UPF0053 protein bbp_300"
FT                   /id="PRO_0000088377"
FT   TRANSMEM        13..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        80..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..145
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        212..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          311..373
FT                   /note="CBS 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
FT   DOMAIN          374..434
FT                   /note="CBS 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00703"
SQ   SEQUENCE   519 AA;  58364 MW;  EF30542E48B5117E CRC64;
     MELFLDPSTW AGLLTLIILE IVLGIDNLVF VAILSEKLPP CKQDKARLIG LSFALFMRLG
     LLALMSWMVT LTSEIISNKY FSFSGRDLIL LFGGLFLLFK ATIELHERLD NDIQKNENNK
     HYAGFWTIVI QIVILDSIFS LDAIITAVGT INNLPIMMIA VVIAMVLMLI ASKPLTKFIN
     LHQTVVVLCL SFLLMIGCNL VSEALGFYVP KGYLYAAIGF SIIIEIFNQI ARRNFMLHQS
     RRPMRQRAAE AILRLMIGDQ FRNTTTNIST KNKDKEKIRN RTTDTESFKE EERYMINGVL
     TLAARSIRSI MTPRNEISWV NIYQPKNKIR SQLLDTPHSL FPVCKGQLDE VIGIVRAKEL
     LVALERTINI IDFSSTTLPI IIPDTLDPIN LLGVLRRAKG SLVIVTNEFG AVQGLITPLD
     VLEAIAGEFP DADETPDIIF EKDSWLVKGG TDLHSLQQCL NITNLIKQEN SYASLAGLLI
     AQKGQLPLPG ETIVIPPLRF YILEATQYRI NLVRITKQH