ID   Y3030_MYCTO             Reviewed;         274 AA.
AC   P9WJZ0; L0TE97; O53277; Q7D695;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 36.
DE   RecName: Full=Probable S-adenosylmethionine-dependent methyltransferase MT3114;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MT3114;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- FUNCTION: Probable S-adenosylmethionine-dependent methyltransferase
CC       required for the 6-O-methylation of the polysaccharide backbone of 6-O-
CC       methylglucosyl lipopolysaccharides (MGLP). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK47444.1; -; Genomic_DNA.
DR   PIR; A70859; A70859.
DR   RefSeq; WP_003415922.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJZ0; -.
DR   SMR; P9WJZ0; -.
DR   EnsemblBacteria; AAK47444; AAK47444; MT3114.
DR   KEGG; mtc:MT3114; -.
DR   PATRIC; fig|83331.31.peg.3356; -.
DR   HOGENOM; CLU_1077241_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR013216; Methyltransf_11.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF08241; Methyltransf_11; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..274
FT                   /note="Probable S-adenosylmethionine-dependent
FT                   methyltransferase MT3114"
FT                   /id="PRO_0000427746"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   274 AA;  29984 MW;  E50314FC7518FD0A CRC64;
     MCAFVPHVPR HSRGDNPPSA STASPAVLTL TGERTIPDLD IENYWFRRHQ VVYQRLAPRC
     TARDVLEAGC GEGYGADLIA CVARQVIAVD YDETAVAHVR SRYPRVEVMQ ANLAELPLPD
     ASVDVVVNFQ VIEHLWDQAR FVRECARVLR GSGLLMVSTP NRITFSPGRD TPINPFHTRE
     LNADELTSLL IDAGFVDVAM CGLFHGPRLR DMDARHGGSI IDAQIMRAVA GAPWPPELAA
     DVAAVTTADF EMVAAGHDRD IDDSLDLIAI AVRP