Y3035_MYCTU
ID Y3035_MYCTU Reviewed; 411 AA.
AC I6XFZ8;
DT 01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-2015, sequence version 2.
DT 03-AUG-2022, entry version 63.
DE RecName: Full=Protein Rv3035;
GN OrderedLocusNames=Rv3035 {ECO:0000312|EMBL:CCP45844.1},
GN RVBD_3035 {ECO:0000312|EMBL:AFN51024.1};
GN ORFNames=P425_03163 {ECO:0000312|EMBL:KBJ29079.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP PROTEIN SEQUENCE OF 50-61, AND SEQUENCE REVISION TO N-TERMINUS.
RC STRAIN=H37Rv;
RX PubMed=34915127; DOI=10.1016/j.ygeno.2021.12.001;
RA Shi J., Meng S., Wan L., Zhang Z., Jiang S., Zhu H., Dai E., Chang L.,
RA Gao H., Wan K., Zhang L., Zhao X., Liu H., Lyu Z., Zhang Y., Xu P.;
RT "Deep N-terminomics of Mycobacterium tuberculosis H37Rv extensively correct
RT annotated encoding genes.";
RL Genomics 114:292-304(2021).
RN [3]
RP IDENTIFICATION, AND GENOME REANNOTATION.
RC STRAIN=ATCC 25618 / H37Rv;
RA Lew J.M.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RG The Broad Institute Genome Sequencing Platform;
RA Galagan J., Kreiswirth B., Dobos K., Fortune S., Fitzgerald M., Young S.K.,
RA Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Berlin A.M., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Mycobacterium tuberculosis H37Rv.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Kreiswirth B., Gomez J., Victor T., Desjardins C., Abeel T.,
RA Young S., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Murphy C., Naylor J., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The genome sequence of Mycobacterium tuberculosis H37Rv.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- CAUTION: The predicted start codon is CTG.
CC {ECO:0000305|PubMed:34915127}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AFN51024.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000269|PubMed:34915127};
CC Sequence=CCP45844.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000269|PubMed:34915127};
CC Sequence=KBJ29079.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000269|PubMed:34915127};
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DR EMBL; AL123456; CCP45844.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP003248; AFN51024.1; ALT_INIT; Genomic_DNA.
DR EMBL; JLDD01000038; KBJ29079.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_217551.1; NC_000962.3.
DR AlphaFoldDB; I6XFZ8; -.
DR SMR; I6XFZ8; -.
DR STRING; 83332.Rv3035; -.
DR PaxDb; I6XFZ8; -.
DR PRIDE; I6XFZ8; -.
DR DNASU; 887842; -.
DR GeneID; 887842; -.
DR KEGG; mtu:Rv3035; -.
DR KEGG; mtv:RVBD_3035; -.
DR PATRIC; fig|83332.111.peg.3382; -.
DR TubercuList; Rv3035; -.
DR eggNOG; COG1520; Bacteria.
DR Proteomes; UP000001584; Chromosome.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR Pfam; PF13360; PQQ_2; 1.
DR SUPFAM; SSF50998; SSF50998; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Reference proteome.
FT CHAIN 1..411
FT /note="Protein Rv3035"
FT /id="PRO_0000432519"
SQ SEQUENCE 411 AA; 42539 MW; B2DDD76D983B97C0 CRC64;
MGGCGSADSW VEAAPAQGWP AQYGDAANSS YTTTNGATNL TLRWTRSVKG SLAAGPALSA
RGYLALNGQT PAGCSLMEWQ NDNNGRQRWC VRLVQGGGFA GPLFDGFDNL YVGQPGAIIS
FPPTQWTRWR QPVIGMPSTP RFLGHGRLLV STHLGQLLVF DTRRGMVVGS PVDLVDGIDP
TDATRGLADC APARPGCPVA AAPAFSSVNG TVVVSVWQPG EPAAKLVGLK YHAEQLVREW
TSDAVSAGVL ASPVLSADGS TVYVNGRDHR LWALNAADGK AKWSAPLGFL AQTPPALTPH
GLIVSGGGPD TALAAFRDAG DHAEGAWRRD DVTALSTASL AGTGVGYTVI SGPNHDGTPG
LSLLVFDPAN GHTVNSYPLP GATGYPVGVS VGNDRRVVTA TSDGQVYSFA P