ID   Y3037_MYCTO             Reviewed;         358 AA.
AC   P9WJZ2; L0TBD0; O53284; Q7D688;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 36.
DE   RecName: Full=Uncharacterized S-adenosylmethionine-dependent methyltransferase MT3122;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MT3122;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE000516; AAK47452.1; -; Genomic_DNA.
DR   PIR; H70859; H70859.
DR   RefSeq; WP_003415940.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WJZ2; -.
DR   SMR; P9WJZ2; -.
DR   EnsemblBacteria; AAK47452; AAK47452; MT3122.
DR   KEGG; mtc:MT3122; -.
DR   PATRIC; fig|83331.31.peg.3364; -.
DR   HOGENOM; CLU_038123_1_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR041497; Thump-like.
DR   Pfam; PF18096; Thump_like; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..358
FT                   /note="Uncharacterized S-adenosylmethionine-dependent
FT                   methyltransferase MT3122"
FT                   /id="PRO_0000427745"
SQ   SEQUENCE   358 AA;  39082 MW;  4E2B5AECDF5259CA CRC64;
     MRARFGDRAP WLVETTLLRR RAAGKLGELC PNVGVSQWLF TDEALQQATA APVARHRARR
     LAGRVVHDAT CSIGTELAAL RELAVRAVGS DIDPVRLAMA RHNLAALGME ADLCRADVLH
     PVTRDAVVVI DPARRSNGRR RFHLADYQPG LGPLLDRYRG RDVVVKCAPG IDFEEVGRLG
     FEGEIEVISY RGGVREACLW SAGLAGSGIR RRASILDSGE QIGDDEPDDC GVRPAGKWIV
     DPDGAVVRAG LVRNYGARHG LWQLDPQIAY LSGDRLPPAL RGFEVLEQLA FDERRLRQVL
     SALDCGAAEI LVRGVAIDPD ALRRRLRLRG SRPLAVVITR IGAGSLSHVT AYVCRPSR