ID   Y3037_MYCTU             Reviewed;         358 AA.
AC   P9WJZ3; L0TBD0; O53284; Q7D688;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=Uncharacterized S-adenosylmethionine-dependent methyltransferase Rv3037c;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=Rv3037c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
CC   -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC       {ECO:0000305}.
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DR   EMBL; AL123456; CCP45846.1; -; Genomic_DNA.
DR   PIR; H70859; H70859.
DR   RefSeq; NP_217553.1; NC_000962.3.
DR   RefSeq; WP_003415940.1; NC_000962.3.
DR   AlphaFoldDB; P9WJZ3; -.
DR   SMR; P9WJZ3; -.
DR   STRING; 83332.Rv3037c; -.
DR   PaxDb; P9WJZ3; -.
DR   DNASU; 888640; -.
DR   GeneID; 888640; -.
DR   KEGG; mtu:Rv3037c; -.
DR   TubercuList; Rv3037c; -.
DR   eggNOG; COG2263; Bacteria.
DR   OMA; LCRADAL; -.
DR   PhylomeDB; P9WJZ3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR041497; Thump-like.
DR   Pfam; PF18096; Thump_like; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; S-adenosyl-L-methionine;
KW   Transferase.
FT   CHAIN           1..358
FT                   /note="Uncharacterized S-adenosylmethionine-dependent
FT                   methyltransferase Rv3037c"
FT                   /id="PRO_0000413013"
SQ   SEQUENCE   358 AA;  39082 MW;  4E2B5AECDF5259CA CRC64;
     MRARFGDRAP WLVETTLLRR RAAGKLGELC PNVGVSQWLF TDEALQQATA APVARHRARR
     LAGRVVHDAT CSIGTELAAL RELAVRAVGS DIDPVRLAMA RHNLAALGME ADLCRADVLH
     PVTRDAVVVI DPARRSNGRR RFHLADYQPG LGPLLDRYRG RDVVVKCAPG IDFEEVGRLG
     FEGEIEVISY RGGVREACLW SAGLAGSGIR RRASILDSGE QIGDDEPDDC GVRPAGKWIV
     DPDGAVVRAG LVRNYGARHG LWQLDPQIAY LSGDRLPPAL RGFEVLEQLA FDERRLRQVL
     SALDCGAAEI LVRGVAIDPD ALRRRLRLRG SRPLAVVITR IGAGSLSHVT AYVCRPSR