ID   Y3055_STRAW             Reviewed;         998 AA.
AC   Q82IS8;
DT   04-AUG-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=UPF0182 protein SAV_3055 {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=SAV_3055;
OS   Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC
OS   14893 / NCIMB 12804 / NRRL 8165 / MA-4680).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=227882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=11572948; DOI=10.1073/pnas.211433198;
RA   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M.,
RA   Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M.;
RT   "Genome sequence of an industrial microorganism Streptomyces avermitilis:
RT   deducing the ability of producing secondary metabolites.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL
RC   8165 / MA-4680;
RX   PubMed=12692562; DOI=10.1038/nbt820;
RA   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T.,
RA   Sakaki Y., Hattori M., Omura S.;
RT   "Complete genome sequence and comparative analysis of the industrial
RT   microorganism Streptomyces avermitilis.";
RL   Nat. Biotechnol. 21:526-531(2003).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; BA000030; BAC70766.1; -; Genomic_DNA.
DR   RefSeq; WP_010984485.1; NZ_JZJK01000090.1.
DR   AlphaFoldDB; Q82IS8; -.
DR   SMR; Q82IS8; -.
DR   STRING; 227882.SAV_3055; -.
DR   EnsemblBacteria; BAC70766; BAC70766; SAVERM_3055.
DR   KEGG; sma:SAVERM_3055; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   Proteomes; UP000000428; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..998
FT                   /note="UPF0182 protein SAV_3055"
FT                   /id="PRO_0000157727"
FT   TRANSMEM        25..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        69..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        120..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        176..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        219..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        266..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        295..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          879..902
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          939..998
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        958..998
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   998 AA;  109308 MW;  285DB720EB862CC0 CRC64;
     MPDRGGGPTG PRIRVGRPSR RVRTLLMTLG VLAVLGMAFV MFAGFWTDWL WYRSVKYSSV
     FTTTLSTKIG LFFVFGLLMA VAVGVNIWLA HRLRPPLSAM SMEQQSLDRY RMGIAPYKKW
     LLLGITSLVG LIAGASASSQ WRTWLMWVNG VPFHQKDPQF HLDVSFYAFD LPWYRFLLGF
     GFAAAVLSLI AAALTHYLYG GLRITSPGAR ATAAATGHLS VLLGIFVALK AVAYWLDRYG
     LAVKSSDFKA TGNWTGLRYV DANAYLPAKT ILFCIAVICA LLFFATLWRR TWQLPVIGFG
     LMVLSAILIG GLYPAIVQKF QVQPNEQAKE APYVEKNLKA TREAYGIDGA KVTEYPGKSD
     TTDKTKLRDD ADATASVRLL DPNVVSPTFQ QLQQMRNYYA FPTNLDVDRY SKDGKDQDTV
     IGLRELNLNG IPKNNWINDH FRYTHGFGVV AAKGTTADSE GRPVFTESDL PSRGDLKAYQ
     QRIYYGEKTS QYSIVGGPQK EIDYSDDSGE KTTSYQGKSG VNLSSPINRA AYAVAFSEPQ
     ILYSGAIGEG SRILYNRTPK ERVEAVAPWL TIDGDAYPAV VDNKIQWIVD AYTTTNGYPY
     ASRTTLGDTT ADSLTANNNQ RAVVAQQNQV NYIRNSVKAT VDAYTGKVTL FEWDTKDPVL
     KTWEKAFPGT VKPKGDIPKS LIDHLRYPQD LFKVQRELLT RYHVKDAQTF LSGSEVWQVP
     DDPSNKSGNA VPPYYLSMKM PDQQAQTFSL TTTLTPNGRD NLSAFMSVNA EAGTSDYGKI
     RILKLPTSRT VDGPKQVQSQ FNSEQDIAES IRLLKGGDSE VEYGNLLTVP LDGGLLYVEP
     VYVRGGGLKY PLLRKVLVTY GGNTAFEDTL DEALNKVFGA DSTTQPPDEG TTKPPTSSNP
     TVQEALNDAQ KAFDAGQEAL KKPDWQAYAK AQKDLEDALK RAEDAQAEAD KASGGSKSGD
     SGKGSGPTSS PSGSASSSPS SSPSSDKSPS SDKSPGSD