Y3067_MYCTU
ID Y3067_MYCTU Reviewed; 181 AA.
AC I6YB21;
DT 01-APR-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-2015, sequence version 2.
DT 25-MAY-2022, entry version 44.
DE RecName: Full=Uncharacterized protein Rv3067;
GN OrderedLocusNames=Rv3067 {ECO:0000312|EMBL:CCP45876.1},
GN RVBD_3067 {ECO:0000312|EMBL:AFN51057.1},
GN LH57_16745 {ECO:0000312|EMBL:AIR15848.1};
GN ORFNames=P425_03195 {ECO:0000312|EMBL:KBJ29111.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP IDENTIFICATION, AND GENOME REANNOTATION.
RC STRAIN=ATCC 25618 / H37Rv;
RA Lew J.M.;
RL Submitted (DEC-2012) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RG The Broad Institute Genome Sequencing Platform;
RA Galagan J., Kreiswirth B., Dobos K., Fortune S., Fitzgerald M., Young S.K.,
RA Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Berlin A.M., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Mycobacterium tuberculosis H37Rv.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Kreiswirth B., Gomez J., Victor T., Desjardins C., Abeel T.,
RA Young S., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Murphy C., Naylor J., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The genome sequence of Mycobacterium tuberculosis H37Rv.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27294 / TMC 102 / H37Rv;
RA Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J.,
RA Monaco A., King S., Sohrabi A.;
RT "Phylogenetic analysis of Mycobacterial species using whole genome
RT sequences.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT mass spectrometry.";
RL Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255}; Single-pass membrane
CC protein {ECO:0000255}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AFN51057.1; Type=Erroneous initiation; Note=Truncated N-terminus.;
CC Sequence=AIR15848.1; Type=Erroneous initiation; Note=Truncated N-terminus.;
CC Sequence=CCP45876.1; Type=Erroneous initiation; Note=Truncated N-terminus.;
CC Sequence=KBJ29111.1; Type=Erroneous initiation; Note=Truncated N-terminus.;
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DR EMBL; AL123456; CCP45876.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP003248; AFN51057.1; ALT_INIT; Genomic_DNA.
DR EMBL; JLDD01000038; KBJ29111.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP009480; AIR15848.1; ALT_INIT; Genomic_DNA.
DR RefSeq; NP_217583.1; NC_000962.3.
DR AlphaFoldDB; I6YB21; -.
DR STRING; 83332.Rv3067; -.
DR PaxDb; I6YB21; -.
DR DNASU; 888822; -.
DR GeneID; 888822; -.
DR KEGG; mtu:Rv3067; -.
DR KEGG; mtv:RVBD_3067; -.
DR PATRIC; fig|83332.111.peg.3417; -.
DR TubercuList; Rv3067; -.
DR eggNOG; ENOG5031HVF; Bacteria.
DR HOGENOM; CLU_144132_0_0_11; -.
DR Proteomes; UP000001584; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007969; DUF732.
DR Pfam; PF05305; DUF732; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..181
FT /note="Uncharacterized protein Rv3067"
FT /id="PRO_0000432520"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 181 AA; 18749 MW; 3F2F7AE6A50643E0 CRC64;
MRDEPPTDTA AAPTTGAAPE IDTAREYEVT AEYQSWRVVW GSAAALLTVG VGIGAAILLG
WFTLAHRHPD QPGAAATPPP AGLTTRSAPT AAPPSTLQSP DLDSVFLGNL HDRGISFTNP
DAAVYNGKMV CTNLGGGMTV QQVVEALQSS SPALGDRTTA YVAVSIRTYC PKYDAVLPPG
S
