ID   Y3073_CERS4             Reviewed;         456 AA.
AC   Q01856; Q3IXU3;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 124.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator RHOS4_30730;
GN   OrderedLocusNames=RHOS4_30730; ORFNames=RSP_3026;
OS   Cereibacter sphaeroides (strain ATCC 17023 / DSM 158 / JCM 6121 / CCUG
OS   31486 / LMG 2827 / NBRC 12203 / NCIMB 8253 / ATH 2.4.1.) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=272943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1400197; DOI=10.1128/jb.174.20.6444-6454.1992;
RA   Neidle E.L., Kaplan S.;
RT   "Rhodobacter sphaeroides rdxA, a homolog of Rhizobium meliloti fixG,
RT   encodes a membrane protein which may bind cytoplasmic [4Fe-4S] clusters.";
RL   J. Bacteriol. 174:6444-6454(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17023 / DSM 158 / JCM 6121 / CCUG 31486 / LMG 2827 / NBRC 12203
RC   / NCIMB 8253 / ATH 2.4.1.;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C.,
RA   Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 2 of Rhodobacter sphaeroides 2.4.1.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000305};
CC   -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC       pyridoxal-phosphate-dependent aminotransferase family. {ECO:0000305}.
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DR   EMBL; M94725; AAA26118.1; -; Genomic_DNA.
DR   EMBL; CP000144; ABA80641.1; -; Genomic_DNA.
DR   PIR; B45728; B45728.
DR   RefSeq; WP_011338979.1; NZ_CP030272.1.
DR   RefSeq; YP_354542.1; NC_007494.2.
DR   AlphaFoldDB; Q01856; -.
DR   SMR; Q01856; -.
DR   EnsemblBacteria; ABA80641; ABA80641; RSP_3026.
DR   KEGG; rsp:RSP_3026; -.
DR   PATRIC; fig|272943.9.peg.3443; -.
DR   eggNOG; COG1167; Bacteria.
DR   OMA; LLMTYQL; -.
DR   PhylomeDB; Q01856; -.
DR   Proteomes; UP000002703; Chromosome 2.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0008483; F:transaminase activity; IEA:UniProtKB-KW.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   CDD; cd07377; WHTH_GntR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR004839; Aminotransferase_I/II.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00155; Aminotran_1_2; 1.
DR   Pfam; PF00392; GntR; 1.
DR   SMART; SM00345; HTH_GNTR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   PROSITE; PS50949; HTH_GNTR; 1.
PE   3: Inferred from homology;
KW   Aminotransferase; DNA-binding; Pyridoxal phosphate; Reference proteome;
KW   Transcription; Transcription regulation; Transferase.
FT   CHAIN           1..456
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   RHOS4_30730"
FT                   /id="PRO_0000050705"
FT   DOMAIN          11..79
FT                   /note="HTH gntR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   DNA_BIND        39..58
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00307"
FT   MOD_RES         295
FT                   /note="N6-(pyridoxal phosphate)lysine"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   456 AA;  48173 MW;  4958E544E6952F6C CRC64;
     MWRPHLVDTA RLKYLGIVDA LEADIRAGRV TPGERLPPQR AIAEALGVDL TTVTRALNEA
     QRRGLVSAQV GRGTFVRDEP AGDEGGGTPL DLSMNIPPQP AEPDLRRILP QGIASILTSP
     RGTLAMHYQE STGAPADRTA AASWLAGRVA GASADRIVVT SGAQAALFAL CALLLGRGDV
     VAAGAVTYPG LKAVAAQQHL ELAPVAMDEQ GILPEAFEAV CRERAPKLLY LIPSIDNPTT
     ATLPADRRRE VAAVARRHGV LLIEDDPYAP LRSERLPALA ELAPELTWHI ATLSKCSTPA
     LRIAYVLAPN AAAAVRLATV LRSSVLMAPP IFAALATRWI TDGTLTALAS AIRAENRQRQ
     SSAASIFSGL DFAADPDGHH LWLHLPQRWR AAEFADHAER AGLAIVPASA FAVSPHPAEA
     VRISLGIAPD RGMLEEGLTQ LSGLLTQPAV GSRAVV