Y3078_ARATH
ID Y3078_ARATH Reviewed; 520 AA.
AC Q9SVM0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 109.
DE RecName: Full=BTB/POZ domain-containing protein At3g50780;
GN OrderedLocusNames=At3g50780; ORFNames=F18B3.60;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP DOMAIN BTB.
RX PubMed=15749712; DOI=10.1074/jbc.m413247200;
RA Gingerich D.J., Gagne J.M., Salter D.W., Hellmann H., Estelle M., Ma L.,
RA Vierstra R.D.;
RT "Cullins 3a and 3b assemble with members of the broad
RT complex/tramtrack/bric-a-brac (BTB) protein family to form essential
RT ubiquitin-protein ligases (E3s) in Arabidopsis.";
RL J. Biol. Chem. 280:18810-18821(2005).
CC -!- FUNCTION: May act as a substrate-specific adapter of an E3 ubiquitin-
CC protein ligase complex (CUL3-RBX1-BTB) which mediates the
CC ubiquitination and subsequent proteasomal degradation of target
CC proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- DOMAIN: The BTB/POZ domain mediates the interaction with some component
CC of ubiquitin ligase complexes. {ECO:0000269|PubMed:15749712}.
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DR EMBL; AL049862; CAB42907.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE78709.1; -; Genomic_DNA.
DR EMBL; CP002686; ANM64756.1; -; Genomic_DNA.
DR EMBL; BT002970; AAO22779.1; -; mRNA.
DR EMBL; BT005113; AAO50646.1; -; mRNA.
DR PIR; T08399; T08399.
DR RefSeq; NP_001326763.1; NM_001339480.1.
DR RefSeq; NP_190647.1; NM_114938.4.
DR AlphaFoldDB; Q9SVM0; -.
DR SMR; Q9SVM0; -.
DR BioGRID; 9560; 1.
DR IntAct; Q9SVM0; 1.
DR STRING; 3702.AT3G50780.1; -.
DR iPTMnet; Q9SVM0; -.
DR PaxDb; Q9SVM0; -.
DR PRIDE; Q9SVM0; -.
DR ProteomicsDB; 232360; -.
DR EnsemblPlants; AT3G50780.1; AT3G50780.1; AT3G50780.
DR EnsemblPlants; AT3G50780.2; AT3G50780.2; AT3G50780.
DR GeneID; 824242; -.
DR Gramene; AT3G50780.1; AT3G50780.1; AT3G50780.
DR Gramene; AT3G50780.2; AT3G50780.2; AT3G50780.
DR KEGG; ath:AT3G50780; -.
DR Araport; AT3G50780; -.
DR TAIR; locus:2077927; AT3G50780.
DR eggNOG; ENOG502QUCJ; Eukaryota.
DR HOGENOM; CLU_025834_0_1_1; -.
DR InParanoid; Q9SVM0; -.
DR OMA; ETLYNSC; -.
DR OrthoDB; 529803at2759; -.
DR PhylomeDB; Q9SVM0; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9SVM0; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SVM0; baseline and differential.
DR Genevisible; Q9SVM0; AT.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR InterPro; IPR038920; BTB/POZ_dom_prot.
DR PANTHER; PTHR31060; PTHR31060; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..520
FT /note="BTB/POZ domain-containing protein At3g50780"
FT /id="PRO_0000408530"
FT DOMAIN 127..196
FT /note="BTB"
FT REGION 43..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 58481 MW; 8A4DF1D3C2D0EAC1 CRC64;
MAEIKNAKVE QRQTKIRNVP VAVTPEGFWC CPSPVAFQKT LKSHNSLTKH KQSSPALQPP
KPEKKPSSTT IRSVIASDET QQNLGSFDTV HSIAVPATVQ ERPQRQKVET LPRKVAIEFG
EPGSSDAKVI LVGKQGFCVK LSVHKKVLVD HSCFFAKKLA EKDSVFACLE IESCEDAELY
VETIGLMYCK DMKQRLMKQN VSRVLRVLKV AELLGFSSCI QSCLDYLEAV PWVGEEEEEK
VISSILRLKT EGVGVTPVLK RVASNAVDPP KETLSRIIEL VLRSKEEKSR REMKSIVLKL
LREQNGANVA DNFNDTIYSS CQTCLDSVLS LFKQASEGEK PETDTKQIAV EADNLTWLLD
VLAERQAAEE FSVTWANQKE LALLHEKLPL MSRYHISRVT SRLFIGIGRG ELLPSKDTRL
LLLTTWLQPL FNDYNWLQHG CRSFDGKLVE EGIGRTILTL PLEDQQSILL SWLGSFLNGG
DGCPNLQRAF EVWWRRSFIR PYSDRQANGS CQTDSTSKEE
