ID   Y3079_MYCS2             Reviewed;         291 AA.
AC   A0QWV7; I7FD86;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Nucleotide-binding protein MSMEG_3079/MSMEI_3001 {ECO:0000255|HAMAP-Rule:MF_00636};
GN   OrderedLocusNames=MSMEG_3079, MSMEI_3001;
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA   Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA   Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT   "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT   mutations or sequencing errors?";
RL   Genome Biol. 8:R20.1-R20.9(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=18955433; DOI=10.1101/gr.081901.108;
RA   Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA   Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT   "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT   and a new MS-based protocol.";
RL   Genome Res. 19:128-135(2009).
CC   -!- FUNCTION: Displays ATPase and GTPase activities. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SIMILARITY: Belongs to the RapZ-like family. {ECO:0000255|HAMAP-
CC       Rule:MF_00636}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AFP39465.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CP000480; ABK72905.1; -; Genomic_DNA.
DR   EMBL; CP001663; AFP39465.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_003894466.1; NZ_SIJM01000002.1.
DR   RefSeq; YP_887395.1; NC_008596.1.
DR   AlphaFoldDB; A0QWV7; -.
DR   SMR; A0QWV7; -.
DR   STRING; 246196.MSMEI_3001; -.
DR   PRIDE; A0QWV7; -.
DR   EnsemblBacteria; ABK72905; ABK72905; MSMEG_3079.
DR   EnsemblBacteria; AFP39465; AFP39465; MSMEI_3001.
DR   GeneID; 66734483; -.
DR   KEGG; msg:MSMEI_3001; -.
DR   KEGG; msm:MSMEG_3079; -.
DR   PATRIC; fig|246196.19.peg.3040; -.
DR   eggNOG; COG1660; Bacteria.
DR   OMA; TVMSFGF; -.
DR   OrthoDB; 1603998at2; -.
DR   Proteomes; UP000000757; Chromosome.
DR   Proteomes; UP000006158; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00636; RapZ_like; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005337; RapZ-like.
DR   PANTHER; PTHR30448; PTHR30448; 1.
DR   Pfam; PF03668; ATP_bind_2; 1.
DR   PIRSF; PIRSF005052; P-loopkin; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; GTP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..291
FT                   /note="Nucleotide-binding protein MSMEG_3079/MSMEI_3001"
FT                   /id="PRO_0000383267"
FT   BINDING         14..21
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
FT   BINDING         65..68
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00636"
SQ   SEQUENCE   291 AA;  31942 MW;  CEF599308FB79FC4 CRC64;
     MESHEGIDVV LVTGLSGAGR GTAAKVLEDL GWYVADNLPP ELIARMVDLG LAAGSRITQL
     AVVMDVRSKG FTGDLDWVRN ELATRNIAPR VLFMEASDDI LVRRYEQNRR SHPLQGTQTL
     AEGIAAERAM LAPVRAAADL VIDTSTLPVP ALRESIERAF GGETVAYTNV TVESFGYKYG
     LPMDADTVMD VRFLPNPHWV DELRPHSGQH PDVRDYVLGQ PGALEFLDTY HRLLDVVIDG
     YRREGKRYMT VAIGCTGGKH RSVAIAEALA ERLEGGDGLT VRVLHRDLGR E