ID   Y3095_MYCTU             Reviewed;         158 AA.
AC   P9WMG3; L0TEB6; O05774; P0A648;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 32.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator Rv3095;
GN   OrderedLocusNames=Rv3095; ORFNames=MTCY164.06;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL123456; CCP45904.1; -; Genomic_DNA.
DR   PIR; F70918; F70918.
DR   RefSeq; NP_217611.1; NC_000962.3.
DR   RefSeq; WP_003416099.1; NZ_NVQJ01000011.1.
DR   AlphaFoldDB; P9WMG3; -.
DR   SMR; P9WMG3; -.
DR   STRING; 83332.Rv3095; -.
DR   PaxDb; P9WMG3; -.
DR   GeneID; 45427091; -.
DR   GeneID; 888679; -.
DR   KEGG; mtu:Rv3095; -.
DR   TubercuList; Rv3095; -.
DR   eggNOG; COG1733; Bacteria.
DR   OMA; KVCYSST; -.
DR   PhylomeDB; P9WMG3; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR002577; HTH_HxlR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01638; HxlR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS51118; HTH_HXLR; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..158
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   Rv3095"
FT                   /id="PRO_0000148890"
FT   DOMAIN          13..110
FT                   /note="HTH hxlR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00435"
SQ   SEQUENCE   158 AA;  17801 MW;  D198B3ADF2F20682 CRC64;
     MAVSDLSHRF EGESVGRALE LVGERWTLLI LREAFFGVRR FGQLARNLGI PRPTLSSRLR
     MLVEVGLFDR VPYSSDPERH EYRLTEAGRD LFAAIVVLMQ WGDEYLPRPE GPPIKLRHHT
     CGEHADPRLI CTHCGEEITA RNVTPEPGPG FKAKLASS