ID   Y311_SHEON              Reviewed;         786 AA.
AC   Q8EJZ5;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=UPF0313 protein SO_0311 {ECO:0000255|HAMAP-Rule:MF_01251};
GN   OrderedLocusNames=SO_0311;
OS   Shewanella oneidensis (strain MR-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Shewanellaceae; Shewanella.
OX   NCBI_TaxID=211586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MR-1;
RX   PubMed=12368813; DOI=10.1038/nbt749;
RA   Heidelberg J.F., Paulsen I.T., Nelson K.E., Gaidos E.J., Nelson W.C.,
RA   Read T.D., Eisen J.A., Seshadri R., Ward N.L., Methe B.A., Clayton R.A.,
RA   Meyer T., Tsapin A., Scott J., Beanan M.J., Brinkac L.M., Daugherty S.C.,
RA   DeBoy R.T., Dodson R.J., Durkin A.S., Haft D.H., Kolonay J.F., Madupu R.,
RA   Peterson J.D., Umayam L.A., White O., Wolf A.M., Vamathevan J.J.,
RA   Weidman J.F., Impraim M., Lee K., Berry K.J., Lee C., Mueller J.,
RA   Khouri H.M., Gill J., Utterback T.R., McDonald L.A., Feldblyum T.V.,
RA   Smith H.O., Venter J.C., Nealson K.H., Fraser C.M.;
RT   "Genome sequence of the dissimilatory metal ion-reducing bacterium
RT   Shewanella oneidensis.";
RL   Nat. Biotechnol. 20:1118-1123(2002).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01251};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine.
CC       {ECO:0000255|HAMAP-Rule:MF_01251};
CC   -!- SIMILARITY: Belongs to the UPF0313 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01251}.
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DR   EMBL; AE014299; AAN53396.1; -; Genomic_DNA.
DR   RefSeq; NP_715951.1; NC_004347.2.
DR   RefSeq; WP_011070679.1; NZ_CP053946.1.
DR   AlphaFoldDB; Q8EJZ5; -.
DR   STRING; 211586.SO_0311; -.
DR   PaxDb; Q8EJZ5; -.
DR   PRIDE; Q8EJZ5; -.
DR   KEGG; son:SO_0311; -.
DR   PATRIC; fig|211586.12.peg.302; -.
DR   eggNOG; COG1032; Bacteria.
DR   HOGENOM; CLU_018288_2_0_6; -.
DR   OMA; TCMYYTG; -.
DR   OrthoDB; 229299at2; -.
DR   PhylomeDB; Q8EJZ5; -.
DR   BioCyc; SONE211586:G1GMP-298-MON; -.
DR   Proteomes; UP000008186; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.80.30.20; -; 1.
DR   HAMAP; MF_01251; UPF0313; 1.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR020612; Methylthiotransferase_CS.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   InterPro; IPR022946; UPF0313.
DR   InterPro; IPR024560; UPF0313_C.
DR   InterPro; IPR013704; UPF0313_N.
DR   PANTHER; PTHR32331; PTHR32331; 1.
DR   Pfam; PF11842; DUF3362; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   Pfam; PF08497; Radical_SAM_N; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01069; UPF0313; 1.
DR   SMART; SM00729; Elp3; 1.
DR   TIGRFAMs; TIGR03904; SAM_YgiQ; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..786
FT                   /note="UPF0313 protein SO_0311"
FT                   /id="PRO_0000076395"
FT   DOMAIN          371..649
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   REGION          669..688
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          698..786
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        703..721
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        729..743
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         385
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         389
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         392
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
SQ   SEQUENCE   786 AA;  87383 MW;  8353E88322ECE6F1 CRC64;
     MQVESTLFSH PKYWAECFGT APFLPMSRKE MEKLGWDSCD IIIVTGDAYV DHPSFGMAVI
     GRMLEAQGYR VGIIAQPDWS SKDAFMQLGR PNLFFGVTAG NMDSMINRYT ADRRIRSDDA
     YTPGDVGGKR PDRAVTVYTQ RCKEAFKDVP VIIGGIEASL RRIAHYDYWS DKVRRSVIFD
     AKADILMYGN AERPLAEVAR RLAAGEAIAD IQDVRGTAVI RKEPMPEWRG MDSRKIDQLH
     KIDPIPNPYG ADDVGCANLS GPSDAKIFDN DAPKPISVQP PRPKPWDKTY VLLPAFEKVS
     EDKYLYAHAS RILHQEQNPG CARALFQPHG DRGVWVNPPA WPLNTDEMDA VFDLPYKRVP
     HPAYGKEKIP AYDMIKTSIN IMRGCFGGCS FCSITEHEGR IIQSRSQESI IKEIKDIQDK
     VPGFTGVISD LGGPTANMYR LGCTSEKAEK TCRRLSCVYP SICGHLGTDH KHTIDLYRAA
     RAVPGIKKIL IASGVRYDLA IEDPAYVKEL VQHHVGGYLK IAPEHTEEGP LSKMMKPGMG
     AYDKFKELFD KFSKEAGKEQ FLIPYFISAH PGTTDEDMLN LALWLKERKF KLDQVQNFYP
     SPMANATTIY HTELNSLKNV KHTSEVVPVP KKGRQRRLHK ALLRYHDPAG WPIIREGLIA
     MGREDLIGNS PNHLVPPEGR NERGPKWMKD ANQGQKALTR FSGNQFDERK GKGDAKGKPS
     ASKPKGPKSG ANAPQSQQPK TSRPGAKAPF GQSGFKGKAE QGKAGQNKAG HQGRAGKASS
     GRQQAK