ID   Y3127_MYCTO             Reviewed;         344 AA.
AC   P9WL06; L0TBX4; O05800; Q7D629;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Uncharacterized protein MT3212;
GN   OrderedLocusNames=MT3212;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
RN   [2]
RP   INDUCTION BY NITRIC OXIDE (NO) AND BY HYPOXIA, AND DORMANCY REGULON.
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12953092; DOI=10.1084/jem.20030205;
RA   Voskuil M.I., Schnappinger D., Visconti K.C., Harrell M.I., Dolganov G.M.,
RA   Sherman D.R., Schoolnik G.K.;
RT   "Inhibition of respiration by nitric oxide induces a Mycobacterium
RT   tuberculosis dormancy program.";
RL   J. Exp. Med. 198:705-713(2003).
CC   -!- INDUCTION: A member of the dormancy regulon. Induced in response to
CC       reduced oxygen tension (hypoxia) and low levels of nitric oxide (NO).
CC       {ECO:0000269|PubMed:12953092}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAK47552.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000516; AAK47552.1; ALT_INIT; Genomic_DNA.
DR   PIR; F70922; F70922.
DR   RefSeq; WP_003416354.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WL06; -.
DR   SMR; P9WL06; -.
DR   EnsemblBacteria; AAK47552; AAK47552; MT3212.
DR   GeneID; 45427112; -.
DR   KEGG; mtc:MT3212; -.
DR   PATRIC; fig|83331.31.peg.3461; -.
DR   HOGENOM; CLU_051479_1_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.109.10; -; 1.
DR   InterPro; IPR000415; Nitroreductase-like.
DR   SUPFAM; SSF55469; SSF55469; 2.
PE   2: Evidence at transcript level;
FT   CHAIN           1..344
FT                   /note="Uncharacterized protein MT3212"
FT                   /id="PRO_0000427562"
FT   REGION          304..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   344 AA;  38521 MW;  9DACAA3495F03770 CRC64;
     MLKNAVLLAC RAPSVHNSQP WRWVAESGSE HTTVHLFVNR HRTVPATDHS GRQAIISCGA
     VLDHLRIAMT AAHWQANITR FPQPNQPDQL ATVEFSPIDH VTAGQRNRAQ AILQRRTDRL
     PFDSPMYWHL FEPALRDAVD KDVAMLDVVS DDQRTRLVVA SQLSEVLRRD DPYYHAELEW
     WTSPFVLAHG VPPDTLASDA ERLRVDLGRD FPVRSYQNRR AELADDRSKV LVLSTPSDTR
     ADALRCGEVL STILLECTMA GMATCTLTHL IESSDSRDIV RGLTRQRGEP QALIRVGIAP
     PLAAVPAPTP RRPLDSVLQI RQTPEKGRNA SDRNARETGW FSPP