ID   Y3135_HAEIE             Reviewed;         551 AA.
AC   A5UBA3;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Putative transport protein CGSHiEE_03135 {ECO:0000255|HAMAP-Rule:MF_01016};
GN   OrderedLocusNames=CGSHiEE_03135;
OS   Haemophilus influenzae (strain PittEE).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=374930;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PittEE;
RX   PubMed=17550610; DOI=10.1186/gb-2007-8-6-r103;
RA   Hogg J.S., Hu F.Z., Janto B., Boissy R., Hayes J., Keefe R., Post J.C.,
RA   Ehrlich G.D.;
RT   "Characterization and modeling of the Haemophilus influenzae core and
RT   supragenomes based on the complete genomic sequences of Rd and 12 clinical
RT   nontypeable strains.";
RL   Genome Biol. 8:R103.1-R103.18(2007).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01016};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01016}.
CC   -!- SIMILARITY: Belongs to the AAE transporter (TC 2.A.81) family. YidE
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_01016}.
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DR   EMBL; CP000671; ABQ98054.1; -; Genomic_DNA.
DR   RefSeq; WP_011961841.1; NC_009566.1.
DR   AlphaFoldDB; A5UBA3; -.
DR   KEGG; hip:CGSHiEE_03135; -.
DR   HOGENOM; CLU_035023_3_1_6; -.
DR   OMA; AMWLIRL; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.30.70.1450; -; 2.
DR   HAMAP; MF_01016; YidE; 1.
DR   InterPro; IPR006037; RCK_C.
DR   InterPro; IPR036721; RCK_C_sf.
DR   InterPro; IPR023018; Transpt_YidE_put.
DR   InterPro; IPR006512; YidE_YbjL.
DR   Pfam; PF06826; Asp-Al_Ex; 2.
DR   Pfam; PF02080; TrkA_C; 1.
DR   SUPFAM; SSF116726; SSF116726; 2.
DR   TIGRFAMs; TIGR01625; YidE_YbjL_dupl; 2.
DR   PROSITE; PS51202; RCK_C; 2.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Repeat; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..551
FT                   /note="Putative transport protein CGSHiEE_03135"
FT                   /id="PRO_1000063251"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        157..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        370..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        402..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        438..458
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        463..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        492..512
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   TRANSMEM        529..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   DOMAIN          191..275
FT                   /note="RCK C-terminal 1"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
FT   DOMAIN          277..360
FT                   /note="RCK C-terminal 2"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01016"
SQ   SEQUENCE   551 AA;  59027 MW;  103AA34966AAE419 CRC64;
     MSDIAITISL LALVAVIGLW IGHWKIRGVG LGIGGVLFGG IIVAHFTDQY GLKLDAHTLH
     FVQEFGLILF VYTIGIQVGP GFFSSLRKSG LKLNAFAILI IVLGSIAVVL VHKIADVPLD
     IALGIYSGAV TNTPALGAGQ QILAELGVPQ TTVTMGVSYA MAYPFGICGI LLAMWLIRLF
     FNVKVDDEAA RFNAESSQDK ESLHNISLKV TNQNLDGLTL IQIPGFSDEE VVCSRLKRDD
     MEIVPKASTE IRTNDILQLV GDDNSLAKMR LIIGYEVDAP TVAYSGEIRS ERVVVTNEKV
     LGKKIRALGI HQKYGVVISR LNRAGIELVP TGNTTLQFGD VLHMVGRSDV LNQAISVIGN
     AQQKLLQVQM LPVFIGIGLG VLVGSIPFYI PGFPVALKLG LAGGPLVVVL ILARIGTIGK
     LYWFMPPSAN LALREIGIVL FLAVVGLKSG GSFFDTLVNG SGLEWMGYGI FITFVPLIIA
     GTIARLYGKL NYLTICGLLA GSMTDPPALA FANEIKEDNG AAALSYATVY PLVMFLRIMS
     PQLLAVLLWA A