ID   Y315_THEM4              Reviewed;         223 AA.
AC   A6LJT6;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=UPF0173 metal-dependent hydrolase Tmel_0315 {ECO:0000255|HAMAP-Rule:MF_00457};
GN   OrderedLocusNames=Tmel_0315;
OS   Thermosipho melanesiensis (strain DSM 12029 / CIP 104789 / BI429).
OC   Bacteria; Thermotogae; Thermotogales; Fervidobacteriaceae; Thermosipho.
OX   NCBI_TaxID=391009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 12029 / CIP 104789 / BI429;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C.,
RA   Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Nelson K., Gogarten J.P., Noll K., Richardson P.;
RT   "Complete sequence of Thermosipho melanesiensis BI429.";
RL   Submitted (MAY-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the UPF0173 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00457}.
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DR   EMBL; CP000716; ABR30187.1; -; Genomic_DNA.
DR   RefSeq; WP_012056548.1; NC_009616.1.
DR   AlphaFoldDB; A6LJT6; -.
DR   SMR; A6LJT6; -.
DR   STRING; 391009.Tmel_0315; -.
DR   EnsemblBacteria; ABR30187; ABR30187; Tmel_0315.
DR   KEGG; tme:Tmel_0315; -.
DR   eggNOG; COG2220; Bacteria.
DR   HOGENOM; CLU_070010_4_0_0; -.
DR   OMA; WHGHSTW; -.
DR   Proteomes; UP000001110; Chromosome.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00457; UPF0173; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR022877; UPF0173.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..223
FT                   /note="UPF0173 metal-dependent hydrolase Tmel_0315"
FT                   /id="PRO_1000013514"
SQ   SEQUENCE   223 AA;  24538 MW;  3025087C83E6D5B2 CRC64;
     MKITFLGHAV FLIEEKRTFL IDPFIKGNPA FPSNYILPDI DYILVTHGHG DHIGDTVELA
     EKYGATVISN FEICNYLQMK GVKKVHPMHI GGVKEFEFGK LKMTPALHGS GIIDGNNIIY
     GGNPGGFLIN LKKSIYHAGD TGLTKDMELL EGVDVALLPI GGNFVMDVND AVKAVEFIKP
     QIVIPMHYNT WDLISADANE FKDKVEKLGV KCVILKPGES LEV