ID   Y316_STRP1              Reviewed;         238 AA.
AC   P67188; Q490T0; Q9A1E6;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=Probable transcriptional regulatory protein SPy_0316/M5005_Spy0269 {ECO:0000255|HAMAP-Rule:MF_00918};
GN   OrderedLocusNames=SPy_0316, M5005_Spy0269;
OS   Streptococcus pyogenes serotype M1.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=301447;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700294 / SF370 / Serotype M1;
RX   PubMed=11296296; DOI=10.1073/pnas.071559398;
RA   Ferretti J.J., McShan W.M., Ajdic D.J., Savic D.J., Savic G., Lyon K.,
RA   Primeaux C., Sezate S., Suvorov A.N., Kenton S., Lai H.S., Lin S.P.,
RA   Qian Y., Jia H.G., Najar F.Z., Ren Q., Zhu H., Song L., White J., Yuan X.,
RA   Clifton S.W., Roe B.A., McLaughlin R.E.;
RT   "Complete genome sequence of an M1 strain of Streptococcus pyogenes.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:4658-4663(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-947 / MGAS5005 / Serotype M1;
RX   PubMed=16088826; DOI=10.1086/432514;
RA   Sumby P., Porcella S.F., Madrigal A.G., Barbian K.D., Virtaneva K.,
RA   Ricklefs S.M., Sturdevant D.E., Graham M.R., Vuopio-Varkila J., Hoe N.P.,
RA   Musser J.M.;
RT   "Evolutionary origin and emergence of a highly successful clone of serotype
RT   M1 group A Streptococcus involved multiple horizontal gene transfer
RT   events.";
RL   J. Infect. Dis. 192:771-782(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00918}.
CC   -!- SIMILARITY: Belongs to the TACO1 family. YeeN subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_00918}.
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DR   EMBL; AE004092; AAK33376.1; -; Genomic_DNA.
DR   EMBL; CP000017; AAZ50888.1; -; Genomic_DNA.
DR   RefSeq; NP_268655.1; NC_002737.2.
DR   AlphaFoldDB; P67188; -.
DR   SMR; P67188; -.
DR   STRING; 1314.HKU360_00308; -.
DR   PaxDb; P67188; -.
DR   EnsemblBacteria; AAK33376; AAK33376; SPy_0316.
DR   KEGG; spy:SPy_0316; -.
DR   KEGG; spz:M5005_Spy0269; -.
DR   PATRIC; fig|160490.10.peg.276; -.
DR   HOGENOM; CLU_062974_2_0_9; -.
DR   OMA; CAKNGGF; -.
DR   Proteomes; UP000000750; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.200; -; 1.
DR   Gene3D; 3.30.70.980; -; 2.
DR   HAMAP; MF_00693; Transcrip_reg_TACO1; 1.
DR   HAMAP; MF_00918; Transcrip_reg_TACO1_YeeN; 1.
DR   InterPro; IPR017856; Integrase-like_N.
DR   InterPro; IPR002876; Transcrip_reg_TACO1-like.
DR   InterPro; IPR026564; Transcrip_reg_TACO1-like_dom3.
DR   InterPro; IPR026562; Transcrip_reg_TACO1_YeeN.
DR   InterPro; IPR029072; YebC-like.
DR   PANTHER; PTHR12532; PTHR12532; 1.
DR   Pfam; PF01709; Transcrip_reg; 1.
DR   SUPFAM; SSF75625; SSF75625; 1.
DR   TIGRFAMs; TIGR01033; TIGR01033; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..238
FT                   /note="Probable transcriptional regulatory protein
FT                   SPy_0316/M5005_Spy0269"
FT                   /id="PRO_0000175906"
SQ   SEQUENCE   238 AA;  25888 MW;  CFF42FE1DED89F9B CRC64;
     MGRKWANIVA KKTAKDGATS KVYAKFGVEI YVAAKQGEPD PELNTALKFV IDRAKQAQVP
     KHVIDKAIDK AKGNTDETFV EGRYEGFGPN GSMIIVDTLT SNVNRTAANV RTAYGKNGGN
     MGASGSVSYL FDKKGVIVFA GDDADSVFEQ LLEADVDVDD VEAEEGTITV YTAPTDLHKG
     IQALRDNGVE EFQVTELEMI PQSEVVLEGD DLETFEKLID ALESDDDVQK VYHNVADF