ID   Y3198_MYCTU             Reviewed;          84 AA.
AC   P9WN17; L0TC42; Q6MX00; Q8VJ51;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Putative glutaredoxin Rv3198.1;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=Rv3198.1; ORFNames=Rv3198A;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR   EMBL; AL123456; CCP46013.1; -; Genomic_DNA.
DR   RefSeq; WP_003416827.1; NZ_NVQJ01000003.1.
DR   RefSeq; YP_177941.1; NC_000962.3.
DR   PDB; 2LQO; NMR; -; A=3-84.
DR   PDB; 2LQQ; NMR; -; A=3-84.
DR   PDBsum; 2LQO; -.
DR   PDBsum; 2LQQ; -.
DR   AlphaFoldDB; P9WN17; -.
DR   BMRB; P9WN17; -.
DR   SMR; P9WN17; -.
DR   STRING; 83332.Rv3198A; -.
DR   PaxDb; P9WN17; -.
DR   DNASU; 3205084; -.
DR   GeneID; 3205084; -.
DR   GeneID; 45427189; -.
DR   KEGG; mtu:Rv3198A; -.
DR   TubercuList; Rv3198A; -.
DR   eggNOG; COG0695; Bacteria.
DR   OMA; EGIAYTE; -.
DR   PhylomeDB; P9WN17; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR   GO; GO:0097573; F:glutathione oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0045454; P:cell redox homeostasis; IBA:GO_Central.
DR   InterPro; IPR011915; GlrX_actino.
DR   InterPro; IPR002109; Glutaredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   Pfam; PF00462; Glutaredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR02200; GlrX_actino; 1.
DR   PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Oxidoreductase; Reference proteome.
FT   CHAIN           1..84
FT                   /note="Putative glutaredoxin Rv3198.1"
FT                   /id="PRO_0000363861"
FT   DOMAIN          1..84
FT                   /note="Glutaredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00686"
FT   STRAND          6..10
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   HELIX           17..26
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   STRAND          32..35
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   TURN            36..38
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   HELIX           40..49
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   STRAND          50..54
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   STRAND          58..61
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   STRAND          66..69
FT                   /evidence="ECO:0007829|PDB:2LQO"
FT   HELIX           72..83
FT                   /evidence="ECO:0007829|PDB:2LQO"
SQ   SEQUENCE   84 AA;  8963 MW;  6E7DD7F00D4CAF3F CRC64;
     MITAALTIYT TSWCGYCLRL KTALTANRIA YDEVDIEHNR AAAEFVGSVN GGNRTVPTVK
     FADGSTLTNP SADEVKAKLV KIAG