ID   Y3226_SACS2             Reviewed;         272 AA.
AC   Q97U03;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   18-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Uncharacterized aldolase SSO3226;
DE            EC=4.2.1.-;
GN   OrderedLocusNames=SSO3226;
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
CC   -!- SIMILARITY: Belongs to the DeoC/FbaB aldolase family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006641; AAK43321.1; -; Genomic_DNA.
DR   PIR; B90508; B90508.
DR   RefSeq; WP_010924169.1; NC_002754.1.
DR   AlphaFoldDB; Q97U03; -.
DR   SMR; Q97U03; -.
DR   STRING; 273057.SSO3226; -.
DR   EnsemblBacteria; AAK43321; AAK43321; SSO3226.
DR   GeneID; 1453240; -.
DR   KEGG; sso:SSO3226; -.
DR   PATRIC; fig|273057.12.peg.3328; -.
DR   eggNOG; arCOG04044; Archaea.
DR   HOGENOM; CLU_057069_2_1_2; -.
DR   InParanoid; Q97U03; -.
DR   OMA; CEYWGMP; -.
DR   PhylomeDB; Q97U03; -.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0004332; F:fructose-bisphosphate aldolase activity; IEA:InterPro.
DR   CDD; cd00958; DhnA; 1.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002915; DeoC/FbaB/LacD_aldolase.
DR   InterPro; IPR041720; FbaB-like.
DR   Pfam; PF01791; DeoC; 1.
DR   PIRSF; PIRSF038992; Aldolase_Ia; 1.
DR   SMART; SM01133; DeoC; 1.
PE   3: Inferred from homology;
KW   Lyase; Reference proteome; Schiff base.
FT   CHAIN           1..272
FT                   /note="Uncharacterized aldolase SSO3226"
FT                   /id="PRO_0000138960"
FT   ACT_SITE        185
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   272 AA;  29916 MW;  875B68CDCD2057E3 CRC64;
     MIGSEIRMAK LFDKGRALVV ALDHGLVMGP LKGIENPVEV VAKIAKNGPD ALQMTPSMVK
     LVKENFFSRG SPMLITRLDT ANVWRQKYKV YNEGYYASIY TVKDAISAGA DAVVTYLVVG
     YGNDTVEGYN LSVLSSLRKE ANDYGIPFIV EPLYVTKDNP DSVKEVDLVK YVTRLASEIG
     ADILKVDYTG NKESFRQVIN VAFSPILIRG GPKTNTTEEF LRMLRDALEA GAKGVTVGRN
     LWQAEEPDKL AKAISKVIHE NADIGEALKI LK