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Y325_HAEIN
ID   Y325_HAEIN              Reviewed;         450 AA.
AC   P44640;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized membrane protein HI_0325;
GN   OrderedLocusNames=HI_0325;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; L42023; AAC21988.1; -; Genomic_DNA.
DR   PIR; A64148; A64148.
DR   RefSeq; NP_438490.1; NC_000907.1.
DR   RefSeq; WP_005694344.1; NC_000907.1.
DR   AlphaFoldDB; P44640; -.
DR   STRING; 71421.HI_0325; -.
DR   EnsemblBacteria; AAC21988; AAC21988; HI_0325.
DR   KEGG; hin:HI_0325; -.
DR   PATRIC; fig|71421.8.peg.342; -.
DR   eggNOG; COG2056; Bacteria.
DR   HOGENOM; CLU_037927_0_0_6; -.
DR   OMA; MMAFIAF; -.
DR   PhylomeDB; P44640; -.
DR   BioCyc; HINF71421:G1GJ1-341-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR   InterPro; IPR032813; Na_H_antiport_N.
DR   Pfam; PF13726; Na_H_antiport_2; 1.
DR   Pfam; PF03553; Na_H_antiporter; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..450
FT                   /note="Uncharacterized membrane protein HI_0325"
FT                   /id="PRO_0000077911"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        242..262
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        267..287
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        378..398
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        428..448
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   450 AA;  47440 MW;  AFD139E73FD6B061 CRC64;
     MLSNPVVISI IVLLALSLLR INVIIALVIA ALTAGFIGDL GLTKTIETFT GGLGGGAEVA
     MNYAILGAFA IAISKSGITD LIAYKIITKM NKTPTAGNLT WFKYFIFAVL ALFAISSQNL
     LPVHIAFIPI VVPPLLSIFN RLKIDRRAVA CVLTFGLTAT YILLPVGFGK IFIESILVKN
     INQAGATLGL QTNVAQVSLA MLLPVIGMIL GLLTAIFITY RKPREYNINV EEATTKDIEA
     HIANIKPKQI VASLIAIVAT FATQLVTSST IIGGLIGLII FVLCGIFKLK ESNDIFQQGL
     RLMAMIGFVM IAASGFANVI NATTGVTDLV QSLSSGVVQS KGIAALLMLV VGLLITMGIG
     SSFSTVPIIT SIYVPLCLSF GFSPLATISI VGVAAALGDA GSPASDSTLG PTSGLNMDGK
     HDHIWDSVVP TFIHYNIPLL VFGWIAAMYL
 
 
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