Y325_HAEIN
ID Y325_HAEIN Reviewed; 450 AA.
AC P44640;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Uncharacterized membrane protein HI_0325;
GN OrderedLocusNames=HI_0325;
OS Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=71421;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX PubMed=7542800; DOI=10.1126/science.7542800;
RA Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT Rd.";
RL Science 269:496-512(1995).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
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DR EMBL; L42023; AAC21988.1; -; Genomic_DNA.
DR PIR; A64148; A64148.
DR RefSeq; NP_438490.1; NC_000907.1.
DR RefSeq; WP_005694344.1; NC_000907.1.
DR AlphaFoldDB; P44640; -.
DR STRING; 71421.HI_0325; -.
DR EnsemblBacteria; AAC21988; AAC21988; HI_0325.
DR KEGG; hin:HI_0325; -.
DR PATRIC; fig|71421.8.peg.342; -.
DR eggNOG; COG2056; Bacteria.
DR HOGENOM; CLU_037927_0_0_6; -.
DR OMA; MMAFIAF; -.
DR PhylomeDB; P44640; -.
DR BioCyc; HINF71421:G1GJ1-341-MON; -.
DR Proteomes; UP000000579; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR InterPro; IPR032813; Na_H_antiport_N.
DR Pfam; PF13726; Na_H_antiport_2; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..450
FT /note="Uncharacterized membrane protein HI_0325"
FT /id="PRO_0000077911"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 242..262
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 302..322
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 343..363
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 378..398
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 428..448
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 450 AA; 47440 MW; AFD139E73FD6B061 CRC64;
MLSNPVVISI IVLLALSLLR INVIIALVIA ALTAGFIGDL GLTKTIETFT GGLGGGAEVA
MNYAILGAFA IAISKSGITD LIAYKIITKM NKTPTAGNLT WFKYFIFAVL ALFAISSQNL
LPVHIAFIPI VVPPLLSIFN RLKIDRRAVA CVLTFGLTAT YILLPVGFGK IFIESILVKN
INQAGATLGL QTNVAQVSLA MLLPVIGMIL GLLTAIFITY RKPREYNINV EEATTKDIEA
HIANIKPKQI VASLIAIVAT FATQLVTSST IIGGLIGLII FVLCGIFKLK ESNDIFQQGL
RLMAMIGFVM IAASGFANVI NATTGVTDLV QSLSSGVVQS KGIAALLMLV VGLLITMGIG
SSFSTVPIIT SIYVPLCLSF GFSPLATISI VGVAAALGDA GSPASDSTLG PTSGLNMDGK
HDHIWDSVVP TFIHYNIPLL VFGWIAAMYL