ID   Y3272_ARATH             Reviewed;         426 AA.
AC   Q9LK31; Q93ZP9;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Kelch repeat-containing protein At3g27220;
GN   OrderedLocusNames=At3g27220; ORFNames=K17E12.4;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA   Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT   features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT   clones.";
RL   DNA Res. 7:217-221(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}.
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DR   EMBL; AP000381; BAB02117.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE77280.1; -; Genomic_DNA.
DR   EMBL; AY048270; AAK82532.1; -; mRNA.
DR   EMBL; BT000591; AAN18160.1; -; mRNA.
DR   EMBL; AY056400; AAL08256.1; -; mRNA.
DR   RefSeq; NP_566812.1; NM_113636.4.
DR   AlphaFoldDB; Q9LK31; -.
DR   SMR; Q9LK31; -.
DR   BioGRID; 7671; 3.
DR   STRING; 3702.AT3G27220.1; -.
DR   PaxDb; Q9LK31; -.
DR   PRIDE; Q9LK31; -.
DR   ProteomicsDB; 232370; -.
DR   EnsemblPlants; AT3G27220.1; AT3G27220.1; AT3G27220.
DR   GeneID; 822341; -.
DR   Gramene; AT3G27220.1; AT3G27220.1; AT3G27220.
DR   KEGG; ath:AT3G27220; -.
DR   Araport; AT3G27220; -.
DR   TAIR; locus:2086528; AT3G27220.
DR   eggNOG; KOG1072; Eukaryota.
DR   HOGENOM; CLU_056092_0_0_1; -.
DR   InParanoid; Q9LK31; -.
DR   OMA; FWNGYLY; -.
DR   OrthoDB; 1562595at2759; -.
DR   PhylomeDB; Q9LK31; -.
DR   PRO; PR:Q9LK31; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LK31; baseline and differential.
DR   Genevisible; Q9LK31; AT.
DR   GO; GO:0005768; C:endosome; HDA:TAIR.
DR   GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR   GO; GO:0005797; C:Golgi medial cisterna; HDA:TAIR.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005802; C:trans-Golgi network; HDA:TAIR.
DR   GO; GO:0009061; P:anaerobic respiration; IMP:TAIR.
DR   GO; GO:0071456; P:cellular response to hypoxia; HEP:TAIR.
DR   Gene3D; 2.120.10.80; -; 2.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   SUPFAM; SSF117281; SSF117281; 2.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Membrane; Reference proteome; Repeat; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..426
FT                   /note="Kelch repeat-containing protein At3g27220"
FT                   /id="PRO_0000300098"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REPEAT          123..170
FT                   /note="Kelch 1"
FT   REPEAT          173..222
FT                   /note="Kelch 2"
FT   REPEAT          224..275
FT                   /note="Kelch 3"
FT   REPEAT          276..338
FT                   /note="Kelch 4"
FT   REPEAT          341..394
FT                   /note="Kelch 5"
FT   CONFLICT        300
FT                   /note="R -> H (in Ref. 3; AAL08256)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   426 AA;  48496 MW;  EAF7A4910790FE5B CRC64;
     MANKPDHHHH HHQSSRRLML VLYFTSVLGI GFIAAFLCLS SSIPSVSAVF SIWVPVNRPE
     IQIPIIDSKI VQKRSKQSND TKDHVRFLSA IFADIPAPEL KWEEMESAPV PRLDGYSVQI
     NNLLYVFSGY GSLDYVHSHV DVFNFTDNKW CDRFHTPKEM ANSHLGIVTD GRYVYVVSGQ
     LGPQCRGPTS RSFVLDSFTK TWLEFPSLPA PRYAPATQIW RGRLHVMGGS KENRNAVAFD
     HWSIAVKDGK ALDEWREEVP IPRGGPHRAC VVANDKLLVI GGQEGDFMAK PNSPIFKCSR
     RREIFNGEVY MMDEEMKWKM LPPMPKNNSH IESAWIIVNN SIVIVGGTTD WHPVTKRLVL
     VGEIFRFQLD TLTWSVIGRL PYRVKTAMAG FWNGYLYFTS GQRDRGPDNP QPGKVIGEMW
     RTKLKF