ID   Y3291_MYCPA             Reviewed;         993 AA.
AC   Q73US5;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=UPF0182 protein MAP_3291c {ECO:0000255|HAMAP-Rule:MF_01600};
GN   OrderedLocusNames=MAP_3291c;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01600};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01600}.
CC   -!- SIMILARITY: Belongs to the UPF0182 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01600}.
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DR   EMBL; AE016958; AAS05841.1; -; Genomic_DNA.
DR   RefSeq; WP_010949913.1; NC_002944.2.
DR   AlphaFoldDB; Q73US5; -.
DR   SMR; Q73US5; -.
DR   STRING; 262316.MAP_3291c; -.
DR   EnsemblBacteria; AAS05841; AAS05841; MAP_3291c.
DR   KEGG; mpa:MAP_3291c; -.
DR   PATRIC; fig|262316.17.peg.3497; -.
DR   eggNOG; COG1615; Bacteria.
DR   HOGENOM; CLU_007733_1_0_11; -.
DR   OMA; HLRYPQD; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01600; UPF0182; 1.
DR   InterPro; IPR005372; UPF0182.
DR   PANTHER; PTHR39344; PTHR39344; 1.
DR   Pfam; PF03699; UPF0182; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..993
FT                   /note="UPF0182 protein MAP_3291c"
FT                   /id="PRO_0000157722"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        113..133
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        254..274
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   TRANSMEM        287..307
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01600"
FT   REGION          903..941
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        916..938
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   993 AA;  107944 MW;  B80D1E5FC18615C2 CRC64;
     MGMRPTARMP KLTRRSRILI LIALGVIALL LAGPRLIDAY VDWLWFGELG YRSVFSTVLV
     TRFVVFLIAG LLVGGIVFAG LAVAYRTRPV FVPSNDNDPV ARYRALVLSR LRLVSVGVPV
     AIGLLAGIIA QSYWVRIQLF LHGGDFGIKD PQFGKDLGFY AFELPFYRLL LSYLFVAVFL
     AFVANLLAHY IFGGIRLSGR TGALSRSARI QLVTLVGLLV LLKAVAYWLD RYELLSHTRG
     GKPITGAGYT DINAVLPAKL ILMAIALICA AAVFSAITMR DLRIPAIGLV LLLLSSLIVG
     AGWPLIVEQI SVKPNAAQKE SEYISRSITA TRQAYGLTSD VVTYRNYTGD AQATAQQVAD
     DRATTSNIRL LDPTIVSPAF TQFQQGKNFY YFPDQLSIDR YLDRNGALRD YVVAVRELNP
     DRLIDNQRDW INRHTVYTHG NGFIASPANT VRGIANDPNQ NGGYPEFLVN VVGANGNVVS
     DGPAPLDQPR VYFGPVISNT SADYAIVGRN GADREYDYET STETKNYTYT GLGGVPIGDW
     LSRSVFAAKF AERNFLFSNV IGSNSKILFN RDPARRVEAV APWLTTDSSV YPAIVNKRLV
     WIIDGYTTLD NYPYSELTSL ESATADSNEV AFNKLAPDKR VSYIRNSVKA TVDAYDGTVT
     LYQQDEQDPV LKAWMQVFPG TVKPKSDISP ELAEHLRYPE DLFKVQRMLL AKYHVNDPVT
     FFSTSDFWDV PLDPNPTASS YQPPYYIVAK NIAKNDNSSS YQLTSAMNRF KRDYLAAYIS
     ASSDPATYGR ITVLTIPGQV NGPKLANNAI TTDPAVSQDL GVIGRDNQNR IRWGNLLTLP
     VGQGGLLYVE PVYASPGASD AASSYPRLIR VAMMYNDKIG YGPTVRDALT GLFGPGAGAA
     ATNIQPTEGG APAASPPANA PAPAVTPGSA PPVAAPPVPD GSVTLSPAKA AVLQEIQAAI
     GAAKDAQKKG DFAGYGAALQ RLDDAITKYN NTK