Y332_THENN
ID Y332_THENN Reviewed; 567 AA.
AC B9KBW2;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=UPF0313 protein CTN_0332 {ECO:0000255|HAMAP-Rule:MF_01251};
GN OrderedLocusNames=CTN_0332;
OS Thermotoga neapolitana (strain ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E).
OC Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga.
OX NCBI_TaxID=309803;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49049 / DSM 4359 / NBRC 107923 / NS-E;
RA Lim S.K., Kim J.S., Cha S.H., Park B.C., Lee D.S., Tae H.S., Kim S.-J.,
RA Kim J.J., Park K.J., Lee S.Y.;
RT "The genome sequence of the hyperthermophilic bacterium Thermotoga
RT neapolitana.";
RL Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01251};
CC Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC cysteines and an exchangeable S-adenosyl-L-methionine.
CC {ECO:0000255|HAMAP-Rule:MF_01251};
CC -!- SIMILARITY: Belongs to the UPF0313 family. {ECO:0000255|HAMAP-
CC Rule:MF_01251}.
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DR EMBL; CP000916; ACM22508.1; -; Genomic_DNA.
DR RefSeq; WP_015918833.1; NC_011978.1.
DR AlphaFoldDB; B9KBW2; -.
DR STRING; 309803.CTN_0332; -.
DR PRIDE; B9KBW2; -.
DR EnsemblBacteria; ACM22508; ACM22508; CTN_0332.
DR KEGG; tna:CTN_0332; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_018288_2_0_0; -.
DR OMA; TCMYYTG; -.
DR Proteomes; UP000000445; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.80.30.20; -; 1.
DR HAMAP; MF_01251; UPF0313; 1.
DR InterPro; IPR006638; Elp3/MiaB/NifB.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR InterPro; IPR022946; UPF0313.
DR InterPro; IPR024560; UPF0313_C.
DR InterPro; IPR013704; UPF0313_N.
DR PANTHER; PTHR32331; PTHR32331; 1.
DR Pfam; PF11842; DUF3362; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF08497; Radical_SAM_N; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01069; UPF0313; 1.
DR SMART; SM00729; Elp3; 1.
DR TIGRFAMs; TIGR03904; SAM_YgiQ; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; S-adenosyl-L-methionine.
FT CHAIN 1..567
FT /note="UPF0313 protein CTN_0332"
FT /id="PRO_1000165088"
FT DOMAIN 288..560
FT /note="Radical SAM core"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT BINDING 303
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_note="4Fe-4S-S-AdoMet"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT BINDING 307
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_note="4Fe-4S-S-AdoMet"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT BINDING 310
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_note="4Fe-4S-S-AdoMet"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
SQ SEQUENCE 567 AA; 64954 MW; 4ACD643376E705F1 CRC64;
MFLPTTREEM KKLGWRELDV ILVTGDAYVD HPSFGVALIG HYLVSHGFKV GIIAQPDWRT
EKDITRLGRP RLFFGVTAGN VDSMVANYTA SKKKRKTDDY TPGGSGGKRP DRATIVYTNL
IKRFFPEVPV VLGGLEASLR RFAHYDWWSE KVRKSILVDS KADLLVYGMG EKAVLEIAQI
LSRTGDIEKC KSVRGVVWWA SQKPEEGIEL PSYDEISENP EKYAEALKLQ TWYTDPYKNI
LIYQKQDTRY VVQNPPQLPL SQEELDRLYL LPFEREVHPF YAKMGRVKAI ETVKFSITAV
RGCFGSCSFC ALTQHQTTHV SYRSKDSILE EVRILTKKKD FKGTITDVGG PTANLYGSSC
SIRETKGQCQ KFCLYPSVCK IVRPNHDEFI SLLESIRKIP GVRNVFVSSG IRHDFVLAEK
DPDVFIRELV KYTPGQLKLA PEHAHPKVLS LMRKPPVELF LEFKKRFETL AKKMGKRKYV
IGYFIVGHPG EGWRENNYLR DFILKHLGYF PQQIQIFTPT PGTVSTAMYY SGLDPFTGEK
VHVERSLKVR NKMKENVLFK KKGREKR
