ID   Y335_MYCAV              Reviewed;         335 AA.
AC   O07395;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=UPF0353 protein MAV335 {ECO:0000255|HAMAP-Rule:MF_01340};
OS   Mycobacterium avium.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=1764;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=GIR10;
RX   PubMed=9534249; DOI=10.1099/00221287-144-3-807;
RA   Labo M., Gusberti L., de Rossi E., Speziale P., Riccardi G.;
RT   "Determination of a 15437 bp nucleotide sequence around the inhA gene of
RT   Mycobacterium avium and similarity analysis of the products of putative
RT   ORFs.";
RL   Microbiology 144:807-814(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC   -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01340}.
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DR   EMBL; AF002133; AAC46199.1; -; Genomic_DNA.
DR   AlphaFoldDB; O07395; -.
DR   SMR; O07395; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.410; -; 1.
DR   HAMAP; MF_01340; UPF0353; 1.
DR   InterPro; IPR022933; UPF0353.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..335
FT                   /note="UPF0353 protein MAV335"
FT                   /id="PRO_0000057642"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   DOMAIN          98..295
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ   SEQUENCE   335 AA;  36054 MW;  58BFF8086A735846 CRC64;
     MSLPFLGPMS LSGFEHSWFF LFLLVVAGLA ALYILMQLAR HGRMLRFANM ELLESVAPKR
     PSTWRHLPAI LLVASLVLFT IAMAGPTNDV RIPRNRAVVM LVIDVSQSMR ATDVAPNRMA
     AAQEAAKQFA DELTPGINLG LIAYAGTATV LVSPTTNREA TKNALDKLQF ADRTATGEGI
     FTALQVQAIA TVGAVIAGDK PPPARIVLFS DGKETMPTNP DNPKGAFTAA RTAKDQGVPI
     STISFGTPYG FVEINDQRQP VPVDDETLKK VAQLSGGNAY NARSLQELKS VYATLQQQIG
     YETIKGDASV GWVRLGALVL RLAADALLIN RRLPT