ID   Y335_TREPA              Reviewed;         180 AA.
AC   O83355;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Uncharacterized protein TP_0335;
GN   OrderedLocusNames=TP_0335;
OS   Treponema pallidum (strain Nichols).
OC   Bacteria; Spirochaetes; Spirochaetales; Treponemataceae; Treponema.
OX   NCBI_TaxID=243276;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nichols;
RX   PubMed=9665876; DOI=10.1126/science.281.5375.375;
RA   Fraser C.M., Norris S.J., Weinstock G.M., White O., Sutton G.G.,
RA   Dodson R.J., Gwinn M.L., Hickey E.K., Clayton R.A., Ketchum K.A.,
RA   Sodergren E., Hardham J.M., McLeod M.P., Salzberg S.L., Peterson J.D.,
RA   Khalak H.G., Richardson D.L., Howell J.K., Chidambaram M., Utterback T.R.,
RA   McDonald L.A., Artiach P., Bowman C., Cotton M.D., Fujii C., Garland S.A.,
RA   Hatch B., Horst K., Roberts K.M., Sandusky M., Weidman J.F., Smith H.O.,
RA   Venter J.C.;
RT   "Complete genome sequence of Treponema pallidum, the syphilis spirochete.";
RL   Science 281:375-388(1998).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; AE000520; AAC65328.1; -; Genomic_DNA.
DR   PIR; E71337; E71337.
DR   AlphaFoldDB; O83355; -.
DR   STRING; 243276.TPANIC_0335; -.
DR   EnsemblBacteria; AAC65328; AAC65328; TP_0335.
DR   KEGG; tpa:TP_0335; -.
DR   HOGENOM; CLU_1502848_0_0_12; -.
DR   OMA; TSCTARV; -.
DR   Proteomes; UP000000811; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0071586; P:CAAX-box protein processing; IEA:InterPro.
DR   InterPro; IPR003675; Rce1-like.
DR   Pfam; PF02517; Rce1-like; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..180
FT                   /note="Uncharacterized protein TP_0335"
FT                   /id="PRO_0000202238"
FT   TRANSMEM        37..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        128..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   180 AA;  19219 MW;  5BB9C80BB334B48A CRC64;
     MAITTAGDIC ALYPLCPILL HCSTLMHLSP LRNTPHVLHA AAAVTEYAFV LSTLVFPSFC
     FSLPSPFPFP EGEGGAFYVR LFLNALSEEV LFRAYIPERL CHHATSCTAR ACGEVLSVLL
     FALAHRPAGS ATLFAGAAGA ALRVLFVREK KRSGSRARAS ALCTAVHALW NAYAIAAAAR