ID   Y3380_DICDI             Reviewed;         561 AA.
AC   Q54BW1;
DT   24-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Putative uncharacterized protein DDB_G0293380;
GN   ORFNames=DDB_G0293380;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   INDUCTION [LARGE SCALE ANALYSIS].
RX   PubMed=18590548; DOI=10.1186/1471-2180-8-109;
RA   Carilla-Latorre S., Calvo-Garrido J., Bloomfield G., Skelton J., Kay R.R.,
RA   Ivens A., Martinez J.L., Escalante R.;
RT   "Dictyostelium transcriptional responses to Pseudomonas aeruginosa: common
RT   and specific effects from PAO1 and PA14 strains.";
RL   BMC Microbiol. 8:109-109(2008).
CC   -!- INDUCTION: Down-regulated by Pseudomonas aeruginosa, PAO1 strain and
CC       PA14 strain infection. {ECO:0000269|PubMed:18590548}.
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DR   EMBL; AAFI02000204; EAL60757.1; -; Genomic_DNA.
DR   RefSeq; XP_629173.1; XM_629171.1.
DR   AlphaFoldDB; Q54BW1; -.
DR   SMR; Q54BW1; -.
DR   STRING; 44689.DDB0302467; -.
DR   PaxDb; Q54BW1; -.
DR   EnsemblProtists; EAL60757; EAL60757; DDB_G0293380.
DR   GeneID; 8629194; -.
DR   KEGG; ddi:DDB_G0293380; -.
DR   dictyBase; DDB_G0293380; -.
DR   eggNOG; ENOG502TMNJ; Eukaryota.
DR   HOGENOM; CLU_486120_0_0_1; -.
DR   InParanoid; Q54BW1; -.
DR   OMA; HTIESTQ; -.
DR   PRO; PR:Q54BW1; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0016423; F:tRNA (guanine) methyltransferase activity; IBA:GO_Central.
DR   GO; GO:0030488; P:tRNA methylation; IBA:GO_Central.
DR   Gene3D; 3.40.50.150; -; 1.
DR   InterPro; IPR000241; RNA_methylase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF01170; UPF0020; 1.
DR   SUPFAM; SSF53335; SSF53335; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..561
FT                   /note="Putative uncharacterized protein DDB_G0293380"
FT                   /id="PRO_0000389017"
FT   COILED          187..217
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   561 AA;  64528 MW;  137CC0232D3A19CA CRC64;
     MKLFITITPN LEKLLHNEIK DILRTNKLTL PKFQVFEGGI EIDLTKDPNI SEQEKEYYLW
     SISNCSRLAE SIRIRVGLSF PCKNFSQFNI NLEKLDYKTY FPTSSIEPQV AVSCNASTLY
     HTNAIKERFI KHFNNSIKDK ISIDINYSKF KPIKKLLKNL RYKLRKIQNP NDDEIIGGGD
     DHEIIGDDEE LSEEEILNRI DKLQIELEQV IGKQKNIPQS KVFIRIDQNV GQLSVDACTS
     GEGQLLHKRT LNKHISDAPI RETLASAIIM AIISSTRRVG SGTTEGSYLD LNKTNIWDPF
     VGSGTLIQEA ISMLLKAKPS SCTNYKRSFQ FERFKNHSTE RYLKYLESIN KPISPLIKNT
     ILIGSDIDQK AIDSSIFNLS KQGYQHENIK FFKGDFKSIY LDQINIDNSL DDDGDNNNNK
     PFTIITNLPY GTRVLNRNQP QQQQNQPIQP KATKIKEGEN YYEDDDDDDF FSIRSPKKDN
     VNIYLNNSIS KDLRDLFKRF GDMIHESNES VLRDVFVLNG NSHFQSISTN NGKNNFEWER
     ILNFRNGGLT VELLKMVKKP N