ID   Y3388_METAC             Reviewed;         424 AA.
AC   Q8TKL5;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Uncharacterized serpin-like protein MA_3388;
GN   OrderedLocusNames=MA_3388;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- SIMILARITY: Belongs to the serpin family. {ECO:0000305}.
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DR   EMBL; AE010299; AAM06757.1; -; Genomic_DNA.
DR   RefSeq; WP_011023315.1; NC_003552.1.
DR   AlphaFoldDB; Q8TKL5; -.
DR   SMR; Q8TKL5; -.
DR   MEROPS; I04.089; -.
DR   EnsemblBacteria; AAM06757; AAM06757; MA_3388.
DR   GeneID; 1475281; -.
DR   KEGG; mac:MA_3388; -.
DR   HOGENOM; CLU_023330_0_2_2; -.
DR   InParanoid; Q8TKL5; -.
DR   OMA; KDVWRGL; -.
DR   OrthoDB; 72278at2157; -.
DR   PhylomeDB; Q8TKL5; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.39.10; -; 1.
DR   Gene3D; 3.30.497.10; -; 1.
DR   InterPro; IPR015557; Serpin_B1.
DR   InterPro; IPR023795; Serpin_CS.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   InterPro; IPR042178; Serpin_sf_1.
DR   InterPro; IPR042185; Serpin_sf_2.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   PANTHER; PTHR11461:SF180; PTHR11461:SF180; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
DR   PROSITE; PS00284; SERPIN; 1.
PE   3: Inferred from homology;
KW   Protease inhibitor; Reference proteome; Serine protease inhibitor.
FT   CHAIN           1..424
FT                   /note="Uncharacterized serpin-like protein MA_3388"
FT                   /id="PRO_0000094162"
FT   SITE            381..382
FT                   /note="Reactive bond"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   424 AA;  48316 MW;  C9059DF00CC89DCC CRC64;
     MNKIKIAFLV FSLILLCTGC IEDKAVVEKN TAVFEESTIN ADSVSDYDIA AANNAFAFDM
     YSQLARRETG DHENVFFSPH SISASMAICY EGAEDTTKEQ ISNVFYFPSN KTVLKVRMER
     INDKINSVNS DYELQTANAL WVQEGYPVKE TYIHNVQKYY DGEVTNLDFA GKPDASRDTI
     NEWVEARTND KIKDLVPEDA ITADARLIIT NAVYFNGKWM YEFDKEMTGK KSFYPTKEED
     ISVDMMYTCN RFNYGETSKA KIIELPYRGN DLSMYVVLPK SNNIEKFETE FTLNDYTELK
     NDMEVVEEVK TTIPKFKFET KTELSNSLIE MGVVDAFGQA DFSGISDSPL EISRVIHQAF
     IDVKEEGTEA AAATMEEMAM GVSISWDAKP KEFTADHPFM FFIEDGRTNC ILFMGKVEYP
     EYEE