ID   Y338_MYCGE              Reviewed;        1270 AA.
AC   P47580;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   31-JAN-2018, sequence version 2.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Uncharacterized lipoprotein MG338;
DE   Flags: Precursor;
GN   OrderedLocusNames=MG338;
OS   Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)
OS   (Mycoplasmoides genitalium).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=243273;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=7569993; DOI=10.1126/science.270.5235.397;
RA   Fraser C.M., Gocayne J.D., White O., Adams M.D., Clayton R.A.,
RA   Fleischmann R.D., Bult C.J., Kerlavage A.R., Sutton G.G., Kelley J.M.,
RA   Fritchman J.L., Weidman J.F., Small K.V., Sandusky M., Fuhrmann J.L.,
RA   Nguyen D.T., Utterback T.R., Saudek D.M., Phillips C.A., Merrick J.M.,
RA   Tomb J.-F., Dougherty B.A., Bott K.F., Hu P.-C., Lucier T.S.,
RA   Peterson S.N., Smith H.O., Hutchison C.A. III, Venter J.C.;
RT   "The minimal gene complement of Mycoplasma genitalium.";
RL   Science 270:397-403(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1022-1113.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=8253680; DOI=10.1128/jb.175.24.7918-7930.1993;
RA   Peterson S.N., Hu P.-C., Bott K.F., Hutchison C.A. III;
RT   "A survey of the Mycoplasma genitalium genome by using random sequencing.";
RL   J. Bacteriol. 175:7918-7930(1993).
RN   [3]
RP   SEQUENCE REVISION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=ATCC 33530 / DSM 19775 / NCTC 10195 / G37;
RX   PubMed=16407165; DOI=10.1073/pnas.0510013103;
RA   Glass J.I., Assad-Garcia N., Alperovich N., Yooseph S., Lewis M.R.,
RA   Maruf M., Hutchison C.A. III, Smith H.O., Venter J.C.;
RT   "Essential genes of a minimal bacterium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:425-430(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00303}; Lipid-anchor {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- DISRUPTION PHENOTYPE: Probably essential, it was not disrupted in a
CC       global transposon mutagenesis study. {ECO:0000269|PubMed:16407165}.
CC   -!- SIMILARITY: Belongs to the MG307/MG309/MG338 family. {ECO:0000305}.
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DR   EMBL; L43967; AAC71563.2; -; Genomic_DNA.
DR   EMBL; U01809; AAD12341.1; -; Genomic_DNA.
DR   PIR; D64237; D64237.
DR   RefSeq; WP_009885969.1; NZ_AAGX01000014.1.
DR   AlphaFoldDB; P47580; -.
DR   STRING; 243273.MG_338; -.
DR   EnsemblBacteria; AAC71563; AAC71563; MG_338.
DR   KEGG; mge:MG_338; -.
DR   eggNOG; ENOG5031Z7V; Bacteria.
DR   HOGENOM; CLU_007912_0_0_14; -.
DR   OMA; YDENAIG; -.
DR   OrthoDB; 5221at2093; -.
DR   Proteomes; UP000000807; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR022186; DUF3713.
DR   Pfam; PF12506; DUF3713; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Coiled coil; Lipoprotein; Membrane; Palmitate;
KW   Reference proteome; Signal.
FT   SIGNAL          1..26
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           27..1270
FT                   /note="Uncharacterized lipoprotein MG338"
FT                   /id="PRO_0000014036"
FT   REGION          942..967
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          92..123
FT                   /evidence="ECO:0000255"
FT   COILED          175..204
FT                   /evidence="ECO:0000255"
FT   LIPID           27
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           27
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   1270 AA;  142391 MW;  8818DD046F763444 CRC64;
     MAHRFKRWSL IALAFSGVGA TAIITACSTI NTANLFPTLN RSQKLIGFSD QNIINPDVVL
     KSALNDGSGV DSILRVSFGS ALQKWYQANA DRNISNRLKI FEENVEDEHD NLIDEKKRAD
     RVKWPIEVQK EYDQFGGNQE SWKKLKLYDR LITDFQSLIF NNISANVSLV NSSDTSVATT
     KENIEKTENK LKFINSNLND VNGDFFTNLQ AYLFSQWLIE ENPFLLNQAS FNYQSPIAGL
     GSIYDENAIG ASNLNLSYNF PAFQDPSESG GQTNSAKLFE EFDKQLQTAN SSGSSQSSAA
     TNTRNDLLDF ENKYSASKVL ISKNNILSVL KTVNLSAAVI DQYHYLLNNK TELTTTTTTT
     TTTGGTSSNL NPLDKFIKSS SATTVMMKSA MTKSQEVTSD NNGFNVKSEF LKINPSLSSS
     GSDNSSNTQS FWKQVQALNN SSQTATIFDA VRMESNSSQA QVVTSNLLVS LSSKTTQKQQ
     QKPVYVRGDD AIYAFHIDGG NYFLENSSPN KRNFEKQAEV LLMRFLQGQT NNFSKDNVSF
     SVDLFGSNSE FRSWANRNTT LKLYTALTTM LENGTSNNNG QKDVCDLAKK LLKNNTNLSE
     TIKKQQDFNN SLSQIKSSYE SYIKAANKLN NFRTDLANIE KLEQAIVDRA NNYIKLQKEA
     KESSIGWGQP LPYKRANDGS YPSLAKFFNN NSDQSSAQTL TLKTTAAAIT SDNEPTREKN
     NQTLKTLTTE VENKAKELVE KWKATTYSSS QYSEIITLKS SQLNDLDLDL ILSLLTDSGI
     RTGTVANIFK NWYFKNTNSF TNNFDTSNKE LKGEFSDFND LVKQALYIRS WQNLTSKERF
     GYYKDLGSVN STSTMLQMQN KAAQSHTSSS VNQTLLDLAK KAFEKELEDP NQDAEYKYMR
     FLQALMWLVK NGAQNYKNLL QQAIPIGTRA FVSWTVGYDK NPSATVSQKT KSSTSSANEN
     PFNRFLQNPN YTQGSEINWF NDKQTPIQPD SLLESENTYR FTDEPFNNSV ALSNKSQGSS
     DKKYFYGFNG LTINSNQSIS TASAGLTQQL FNNYGQLITA TDKAGALSQY KDKFTLWSLI
     NKTSSDAELN AFGELLHRSV NVDTNNLSRF NSRGEPLISF DNKKKFLLNV VDRLDDLYFH
     KFEGYVGLSK AANTDGSNTE GYKTVQTVPL TNDSSIQTLS YVIQITNDDV NKISSNWKNN
     KANSLGLKKE IFMSLLIEQA LDEGTQELAF LDLIRENQKQ HQREHQQILV GDKRLYDILG
     QTLAINAKNF