ID   Y340_MYCPN              Reviewed;         529 AA.
AC   P75438;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Probable DNA helicase MPN_340;
DE            EC=3.6.4.12;
GN   OrderedLocusNames=MPN_340; ORFNames=H91_orf529, MP496;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC   -!- SIMILARITY: Belongs to the helicase family. UvrD subfamily.
CC       {ECO:0000305}.
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DR   EMBL; U00089; AAB96144.1; -; Genomic_DNA.
DR   PIR; S73822; S73822.
DR   RefSeq; NP_110028.1; NC_000912.1.
DR   RefSeq; WP_010874696.1; NC_000912.1.
DR   AlphaFoldDB; P75438; -.
DR   SMR; P75438; -.
DR   IntAct; P75438; 4.
DR   STRING; 272634.MPN_340; -.
DR   PRIDE; P75438; -.
DR   EnsemblBacteria; AAB96144; AAB96144; MPN_340.
DR   KEGG; mpn:MPN_340; -.
DR   PATRIC; fig|272634.6.peg.364; -.
DR   HOGENOM; CLU_004585_6_1_14; -.
DR   OMA; FRTFHDS; -.
DR   BioCyc; MPNE272634:G1GJ3-537-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR   Gene3D; 1.10.10.160; -; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR013986; DExx_box_DNA_helicase_dom_sf.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070; PTHR11070; 2.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   3: Inferred from homology;
KW   ATP-binding; DNA-binding; Helicase; Hydrolase; Nucleotide-binding;
KW   Reference proteome.
FT   CHAIN           1..529
FT                   /note="Probable DNA helicase MPN_340"
FT                   /id="PRO_0000102082"
FT   DOMAIN          2..285
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00560"
FT   BINDING         23..30
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   529 AA;  60529 MW;  D80152E4C58DF32A CRC64;
     MEHLNQEQKA AVTCDNGVNV VYSGAGTGKT TVIAERFAYL VNEKGVNPQS ILAFTFTDKA
     ASEMRQRIIK LIPQKSLQDL HIYTFHSFAN RFLQKHGKSD FAILSDSNRF FSDYEMGDQL
     QTVVEIYKNK VVDLELDNLE YNSAFRDACT DTFNEDFSTI SNGQFRKRAA TALRAYQNYL
     ITNNLFDFSD LIIETCHLLK GNSELLQAFT ESVHYILVDE FQDTNLAQYE LVKLLATTHP
     NLFLVGDSNQ MIYGWRGAVV EIFELLKNDF QAVKEFYTTQ NYRSIQAVLA VANDVLTAIA
     RKERKALVLL HSSIDSKAVP VHYKANSLKN QDQWIIYQMK QLHLNNGVPY DQMAVLFRKN
     KHLDAFSQTV LEDGDLPLAK LNLLTIHAAK GLEFEAVFVY GLVERAFPSL HWDGSDKHKL
     LEEMKLFYVA ITRAKQFLFL VSVSVESFNA YYEPSRFLKL IEKEHLQTQK AAYFKEQLKT
     QPKPVNLYTE TENAENLQKA TDSKKWIILG AILLIIVIIT AVLKLFVEN