ID   Y3410_MYCTO             Reviewed;         375 AA.
AC   P9WKI4; L0TE22; P65170; Q50716;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Uncharacterized oxidoreductase MT3518;
DE            EC=1.-.-.-;
GN   Name=guaB3; OrderedLocusNames=MT3518;
OS   Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83331;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC 1551 / Oshkosh;
RX   PubMed=12218036; DOI=10.1128/jb.184.19.5479-5490.2002;
RA   Fleischmann R.D., Alland D., Eisen J.A., Carpenter L., White O.,
RA   Peterson J.D., DeBoy R.T., Dodson R.J., Gwinn M.L., Haft D.H., Hickey E.K.,
RA   Kolonay J.F., Nelson W.C., Umayam L.A., Ermolaeva M.D., Salzberg S.L.,
RA   Delcher A., Utterback T.R., Weidman J.F., Khouri H.M., Gill J., Mikula A.,
RA   Bishai W., Jacobs W.R. Jr., Venter J.C., Fraser C.M.;
RT   "Whole-genome comparison of Mycobacterium tuberculosis clinical and
RT   laboratory strains.";
RL   J. Bacteriol. 184:5479-5490(2002).
CC   -!- SIMILARITY: Belongs to the IMPDH/GMPR family. {ECO:0000305}.
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DR   EMBL; AE000516; AAK47856.1; -; Genomic_DNA.
DR   PIR; G70736; G70736.
DR   RefSeq; WP_003418005.1; NZ_KK341227.1.
DR   AlphaFoldDB; P9WKI4; -.
DR   SMR; P9WKI4; -.
DR   EnsemblBacteria; AAK47856; AAK47856; MT3518.
DR   GeneID; 45427406; -.
DR   KEGG; mtc:MT3518; -.
DR   PATRIC; fig|83331.31.peg.3776; -.
DR   HOGENOM; CLU_064068_0_0_11; -.
DR   Proteomes; UP000001020; Chromosome.
DR   GO; GO:0003938; F:IMP dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006164; P:purine nucleotide biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR005990; IMP_DH.
DR   InterPro; IPR005992; IMP_DH-rel2.
DR   InterPro; IPR001093; IMP_DH_GMPRt.
DR   PANTHER; PTHR11911; PTHR11911; 1.
DR   PANTHER; PTHR11911:SF85; PTHR11911:SF85; 1.
DR   Pfam; PF00478; IMPDH; 1.
DR   TIGRFAMs; TIGR01304; IMP_DH_rel_2; 1.
PE   3: Inferred from homology;
KW   NAD; Oxidoreductase.
FT   CHAIN           1..375
FT                   /note="Uncharacterized oxidoreductase MT3518"
FT                   /id="PRO_0000427648"
SQ   SEQUENCE   375 AA;  38991 MW;  221116AC214D9741 CRC64;
     MVEIGMGRTA RRTYELSEIS IVPSRRTRSS KDVSTAWQLD AYRFEIPVVA HPTDALVSPE
     FAIELGRLGG LGVLNGEGLI GRHLDVEAKI AQLLEAAAAD PEPSTAIRLL QELHAAPLNP
     DLLGAAVARI REAGVTTAVR VSPQNAQWLT PVLVAAGIDL LVIQGTIVSA ERVASDGEPL
     NLKTFISELD IPVVAGGVLD HRTALHLMRT GAAGVIVGYG STQGVTTTDE VLGISVPMAT
     AIADAAAARR DYLDETGGRY VHVLADGDIH TSGELAKAIA CGADAVVLGT PLAESAEALG
     EGWFWPAAAA HPSLPRGALL QIAVGERPPL ARVLGGPSDD PFGGLNLVGG LRRSMAKAGY
     CDLKEFQKVG LTVGG