ID   Y3414_RALSO             Reviewed;         306 AA.
AC   Q8XTY1;
DT   21-FEB-2002, integrated into UniProtKB/Swiss-Prot.
DT   21-FEB-2002, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=UPF0187 protein RSc3414;
GN   OrderedLocusNames=RSc3414; ORFNames=RS01793;
OS   Ralstonia solanacearum (strain GMI1000) (Pseudomonas solanacearum).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Ralstonia.
OX   NCBI_TaxID=267608;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GMI1000;
RX   PubMed=11823852; DOI=10.1038/415497a;
RA   Salanoubat M., Genin S., Artiguenave F., Gouzy J., Mangenot S., Arlat M.,
RA   Billault A., Brottier P., Camus J.-C., Cattolico L., Chandler M.,
RA   Choisne N., Claudel-Renard C., Cunnac S., Demange N., Gaspin C., Lavie M.,
RA   Moisan A., Robert C., Saurin W., Schiex T., Siguier P., Thebault P.,
RA   Whalen M., Wincker P., Levy M., Weissenbach J., Boucher C.A.;
RT   "Genome sequence of the plant pathogen Ralstonia solanacearum.";
RL   Nature 415:497-502(2002).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0187 family. {ECO:0000305}.
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DR   EMBL; AL646052; CAD16911.1; -; Genomic_DNA.
DR   RefSeq; WP_011003294.1; NC_003295.1.
DR   AlphaFoldDB; Q8XTY1; -.
DR   SMR; Q8XTY1; -.
DR   EnsemblBacteria; CAD16911; CAD16911; RSc3414.
DR   GeneID; 60502927; -.
DR   KEGG; rso:RSc3414; -.
DR   PATRIC; fig|267608.8.peg.3472; -.
DR   eggNOG; COG3781; Bacteria.
DR   HOGENOM; CLU_029790_4_2_4; -.
DR   OMA; WFRMLLA; -.
DR   Proteomes; UP000001436; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005254; F:chloride channel activity; IEA:InterPro.
DR   InterPro; IPR021134; Bestrophin/UPF0187.
DR   InterPro; IPR044669; UPF0187.
DR   PANTHER; PTHR33281; PTHR33281; 1.
DR   Pfam; PF01062; Bestrophin; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..306
FT                   /note="UPF0187 protein RSc3414"
FT                   /id="PRO_0000217669"
FT   TRANSMEM        21..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   306 AA;  34466 MW;  A5DB2BCCBF842207 CRC64;
     MVVRPHLHWF RMLLAWRGSV LPQLLPRLFL IFCISLVAMA VHVHWLPITV NLSTTPFSLI
     GIALAVFLGF RNNASYDRYW EARKLWGQLL NDARSMTRQA LTLPRETLAA ADVREFVQVL
     GALPHALRHQ LRRTDPRDDL SARLPAPLFE RVMASRYRPA ALMLWLGEWV RQRSREGSLD
     AWAVLAFDRN LGSLSNVIGG CERIVSTPLP FAYSVMIHRT VYFFCAALPF GLVESIGNFT
     PVFSVFVAYA FMAHEAIAAQ IEEPFGTEDN DLALNTMSLM IEDAVRDLIG EPSLGDEAAA
     RAFILD