ID   Y3434_MYCPA             Reviewed;         330 AA.
AC   Q73UD4;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=UPF0353 protein MAP_3434 {ECO:0000255|HAMAP-Rule:MF_01340};
GN   OrderedLocusNames=MAP_3434;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC   -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01340}.
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DR   EMBL; AE016958; AAS05984.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q73UD4; -.
DR   SMR; Q73UD4; -.
DR   STRING; 262316.MAP_3434; -.
DR   EnsemblBacteria; AAS05984; AAS05984; MAP_3434.
DR   KEGG; mpa:MAP_3434; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_024570_2_0_11; -.
DR   OMA; WPQMLWL; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.410; -; 1.
DR   HAMAP; MF_01340; UPF0353; 1.
DR   InterPro; IPR022933; UPF0353.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13519; VWA_2; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..330
FT                   /note="UPF0353 protein MAP_3434"
FT                   /id="PRO_0000057646"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        63..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   DOMAIN          94..289
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ   SEQUENCE   330 AA;  34988 MW;  AAA974CC292103DC CRC64;
     MGVVSLPGIG PLPLYGFQRP GMLLFGLVPL ALLALYLVVQ ARRRRRLHRY TDAPVAQSPW
     RHLPIAVSLL SLVLLTIALA TPTHDMRIPR NRAVIMLVID MSQSMRATDV EPNRLKAAEQ
     AASQFASQLT PGINLGLVGF AGTPYLLVPP TPQHQATIDA LKKLDFADST ATGEAIFTAL
     HAISATAVAG GDTPPPARIV LLSDGGENKP SNPSDPHDGV YTAARLAKDE GVPISTITFG
     TKGGEIEMDG QKVAVPVSTD QMKMVAKLSG GQSYTATNLG ELQKSYNAIE NEIGYRTVPG
     PGSAGWLRLG VLTALIATAL ALLINRRLPT