ID   Y3478_NOCFA             Reviewed;         335 AA.
AC   Q5YU15;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=UPF0353 protein NFA_34780 {ECO:0000255|HAMAP-Rule:MF_01340};
GN   OrderedLocusNames=NFA_34780;
OS   Nocardia farcinica (strain IFM 10152).
OC   Bacteria; Actinobacteria; Corynebacteriales; Nocardiaceae; Nocardia.
OX   NCBI_TaxID=247156;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IFM 10152;
RX   PubMed=15466710; DOI=10.1073/pnas.0406410101;
RA   Ishikawa J., Yamashita A., Mikami Y., Hoshino Y., Kurita H., Hotta K.,
RA   Shiba T., Hattori M.;
RT   "The complete genomic sequence of Nocardia farcinica IFM 10152.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:14925-14930(2004).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_01340};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_01340}.
CC   -!- SIMILARITY: Belongs to the UPF0353 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01340}.
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DR   EMBL; AP006618; BAD58326.1; -; Genomic_DNA.
DR   RefSeq; WP_011210011.1; NC_006361.1.
DR   AlphaFoldDB; Q5YU15; -.
DR   SMR; Q5YU15; -.
DR   STRING; 247156.NFA_34780; -.
DR   EnsemblBacteria; BAD58326; BAD58326; NFA_34780.
DR   GeneID; 61134180; -.
DR   KEGG; nfa:NFA_34780; -.
DR   eggNOG; COG2304; Bacteria.
DR   HOGENOM; CLU_024570_2_0_11; -.
DR   OMA; RYFRATD; -.
DR   Proteomes; UP000006820; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.40.50.410; -; 1.
DR   HAMAP; MF_01340; UPF0353; 1.
DR   InterPro; IPR024163; Aerotolerance_reg_N.
DR   InterPro; IPR022933; UPF0353.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF07584; BatA; 1.
DR   Pfam; PF00092; VWA; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..335
FT                   /note="UPF0353 protein NFA_34780"
FT                   /id="PRO_0000057649"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   TRANSMEM        310..330
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
FT   DOMAIN          90..295
FT                   /note="VWFA"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01340"
SQ   SEQUENCE   335 AA;  35887 MW;  82CF1CB3A72F75A2 CRC64;
     MSISHFTALI WLGFLAVVAL IALGYVLVQR SRHRQMLRFS NMEVLEKVAP SRPSPLRHAP
     IALMLVGLVF LTIAAAGPTS VQKVPRNRAT VVLVMDVSLS MEATDVPPSR LEVAQQAGKE
     FVDGLTQGIN LGFVTFAGTA SVMQSPTTNR EAVKAAIDNI KLAERTATGE GILTALQSIE
     TLATVLGGAE TPPPARIVLM SDGKQTVPDD KDVDNPRHAF TAARLAKSKG IPVSTISFGT
     EWGSVEIPDQ DGQGGSQRVK VPVDNESLRE IAKLSGGEFY TASSLEELTA VYDTLEEQIG
     YETTRGDASR PWLLLGMLVV AAGIVTGLLY RQRLP