Y349_MYCPN
ID Y349_MYCPN Reviewed; 281 AA.
AC P75429;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Putative phosphatase/phosphodiesterase MPN_349 {ECO:0000305};
DE EC=3.1.-.- {ECO:0000305};
GN OrderedLocusNames=MPN_349; ORFNames=H91_orf281, MP487;
OS Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS pneumoniae).
OC Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=272634;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29342 / M129;
RX PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT pneumoniae.";
RL Nucleic Acids Res. 24:4420-4449(1996).
RN [2] {ECO:0007744|PDB:1T71}
RP X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH IRON, AND COFACTOR.
RA Shin D.H., Jancarik J., Kim R., Yokota H., Kim S.-H.;
RT "Crystal structure of a novel phosphatase from Mycoplasma pneumoniae.";
RL Submitted (MAY-2004) to the PDB data bank.
CC -!- COFACTOR:
CC Name=Fe(3+); Xref=ChEBI:CHEBI:29034; Evidence={ECO:0000305|Ref.2};
CC -!- SIMILARITY: Belongs to the YmdB-like family. {ECO:0000305}.
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DR EMBL; U00089; AAB96135.1; -; Genomic_DNA.
DR PIR; S73813; S73813.
DR RefSeq; NP_110037.1; NC_000912.1.
DR RefSeq; WP_010874705.1; NC_000912.1.
DR PDB; 1T71; X-ray; 2.10 A; A=1-281.
DR PDBsum; 1T71; -.
DR AlphaFoldDB; P75429; -.
DR SMR; P75429; -.
DR IntAct; P75429; 1.
DR STRING; 272634.MPN_349; -.
DR EnsemblBacteria; AAB96135; AAB96135; MPN_349.
DR GeneID; 66608994; -.
DR KEGG; mpn:MPN_349; -.
DR PATRIC; fig|272634.6.peg.376; -.
DR HOGENOM; CLU_068238_0_0_14; -.
DR OMA; NHIWDKK; -.
DR BioCyc; MPNE272634:G1GJ3-551-MON; -.
DR EvolutionaryTrace; P75429; -.
DR Proteomes; UP000000808; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR005235; YmdB-like.
DR PANTHER; PTHR36303; PTHR36303; 1.
DR Pfam; PF13277; YmdB; 1.
DR PIRSF; PIRSF004789; DR1281; 1.
DR SUPFAM; SSF56300; SSF56300; 1.
DR TIGRFAMs; TIGR00282; TIGR00282; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Hydrolase; Iron; Metal-binding; Reference proteome.
FT CHAIN 1..281
FT /note="Putative phosphatase/phosphodiesterase MPN_349"
FT /id="PRO_0000210486"
FT ACT_SITE 72
FT /note="Proton donor"
FT /evidence="ECO:0000250|UniProtKB:O31775"
FT BINDING 12
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT BINDING 43
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT BINDING 43
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT BINDING 44
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT BINDING 71
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT BINDING 158
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT BINDING 183
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="2"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT BINDING 185
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_label="1"
FT /evidence="ECO:0000269|Ref.2, ECO:0007744|PDB:1T71"
FT STRAND 6..10
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 12..14
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 15..23
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 26..33
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 36..41
FT /evidence="ECO:0007829|PDB:1T71"
FT TURN 45..48
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 53..62
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 66..68
FT /evidence="ECO:0007829|PDB:1T71"
FT TURN 71..74
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 77..79
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 80..83
FT /evidence="ECO:0007829|PDB:1T71"
FT TURN 100..103
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 104..112
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 117..124
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 137..145
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 151..158
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 162..172
FT /evidence="ECO:0007829|PDB:1T71"
FT TURN 173..175
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 176..186
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 199..202
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 206..208
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 219..226
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 241..249
FT /evidence="ECO:0007829|PDB:1T71"
FT TURN 252..254
FT /evidence="ECO:0007829|PDB:1T71"
FT STRAND 259..267
FT /evidence="ECO:0007829|PDB:1T71"
FT HELIX 270..272
FT /evidence="ECO:0007829|PDB:1T71"
SQ SEQUENCE 281 AA; 31431 MW; 909EE2FC9141C2CD CRC64;
MMNSIKFIFL GDVYGKAGRN IIKNNLAQLK SKYQADLVIV NAENTTHGKG LSLKHYEFLK
EAGVNYITMG NHTWFQKLDL AVVINKKDLV RPLNLDTSFA FHNLGQGSLV FEFNKAKIRI
TNLLGTSVPL PFKTTNPFKV LKELILKRDC DLHIVDFHAE TTSEKNAFCM AFDGYVTTIF
GTHTHVPSAD LRITPKGSAY ITDVGMCGPG FGSVIGANPE QSIRLFCAGS REHFEVSKCG
AQLNGVFFEV DVNTKKVIKT EAIRIVEDDP RYLKQDYFNL I
