ID   Y3503_DICDI             Reviewed;          57 AA.
AC   Q54R36;
DT   23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Uncharacterized protein DDB_G0283503;
GN   ORFNames=DDB_G0283503;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=12796308; DOI=10.1128/ec.2.3.627-637.2003;
RA   Maeda M., Sakamoto H., Iranfar N., Fuller D., Maruo T., Ogihara S.,
RA   Morio T., Urushihara H., Tanaka Y., Loomis W.F.;
RT   "Changing patterns of gene expression in Dictyostelium prestalk cell
RT   subtypes recognized by in situ hybridization with genes from microarray
RT   analyses.";
RL   Eukaryot. Cell 2:627-637(2003).
RN   [3]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=15470253; DOI=10.1128/ec.3.5.1241-1248.2004;
RA   Maruo T., Sakamoto H., Iranfar N., Fuller D., Morio T., Urushihara H.,
RA   Tanaka Y., Maeda M., Loomis W.F.;
RT   "Control of cell type proportioning in Dictyostelium discoideum by
RT   differentiation-inducing factor as determined by in situ hybridization.";
RL   Eukaryot. Cell 3:1241-1248(2004).
RN   [4]
RP   IDENTIFICATION.
RX   PubMed=15470642; DOI=10.1387/ijdb.041862ns;
RA   Shimada N., Maeda M., Urushihara H., Kawata T.;
RT   "Identification of new modes of Dd-STATa regulation of gene expression in
RT   Dictyostelium by in situ hybridisation.";
RL   Int. J. Dev. Biol. 48:679-682(2004).
RN   [5]
RP   DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX   PubMed=16024295; DOI=10.1016/j.modgep.2005.04.017;
RA   Yamada Y., Sakamoto H., Ogihara S., Maeda M.;
RT   "Novel patterns of the gene expression regulation in the prestalk region
RT   along the antero-posterior axis during multicellular development of
RT   Dictyostelium.";
RL   Gene Expr. Patterns 6:63-68(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in prestalk pstA and pstO cells in the
CC       slug stage. Preferentially restricted to pstO cells during culmination.
CC       Expression in the prestalk cells is reduced in dmtA-null cells.
CC       {ECO:0000269|PubMed:12796308, ECO:0000269|PubMed:15470253,
CC       ECO:0000269|PubMed:16024295}.
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DR   EMBL; AAFI02000055; EAL65736.1; -; Genomic_DNA.
DR   RefSeq; XP_639055.1; XM_633963.1.
DR   AlphaFoldDB; Q54R36; -.
DR   STRING; 44689.DDB0229989; -.
DR   PaxDb; Q54R36; -.
DR   EnsemblProtists; EAL65736; EAL65736; DDB_G0283503.
DR   GeneID; 8624080; -.
DR   KEGG; ddi:DDB_G0283503; -.
DR   dictyBase; DDB_G0283503; -.
DR   HOGENOM; CLU_210588_0_0_1; -.
DR   PhylomeDB; Q54R36; -.
DR   PRO; PR:Q54R36; -.
DR   Proteomes; UP000002195; Chromosome 4.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..57
FT                   /note="Uncharacterized protein DDB_G0283503"
FT                   /id="PRO_0000392660"
FT   TRANSMEM        34..54
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   57 AA;  5793 MW;  9AC2D988D4D8F1DD CRC64;
     MLFKSLQSIT SVNSIQKNQI SSVSVGSSQS NNNAALLDAA ALVVIPGLLT VAAVAHI