Y3507_DICDI
ID Y3507_DICDI Reviewed; 57 AA.
AC Q54R34;
DT 23-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 1.
DT 25-MAY-2022, entry version 46.
DE RecName: Full=Uncharacterized protein DDB_G0283507;
GN ORFNames=DDB_G0283507;
OS Dictyostelium discoideum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=44689;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AX4;
RX PubMed=15875012; DOI=10.1038/nature03481;
RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT "The genome of the social amoeba Dictyostelium discoideum.";
RL Nature 435:43-57(2005).
RN [2]
RP DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX PubMed=12796308; DOI=10.1128/ec.2.3.627-637.2003;
RA Maeda M., Sakamoto H., Iranfar N., Fuller D., Maruo T., Ogihara S.,
RA Morio T., Urushihara H., Tanaka Y., Loomis W.F.;
RT "Changing patterns of gene expression in Dictyostelium prestalk cell
RT subtypes recognized by in situ hybridization with genes from microarray
RT analyses.";
RL Eukaryot. Cell 2:627-637(2003).
RN [3]
RP DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX PubMed=15470253; DOI=10.1128/ec.3.5.1241-1248.2004;
RA Maruo T., Sakamoto H., Iranfar N., Fuller D., Morio T., Urushihara H.,
RA Tanaka Y., Maeda M., Loomis W.F.;
RT "Control of cell type proportioning in Dictyostelium discoideum by
RT differentiation-inducing factor as determined by in situ hybridization.";
RL Eukaryot. Cell 3:1241-1248(2004).
RN [4]
RP IDENTIFICATION.
RX PubMed=15470642; DOI=10.1387/ijdb.041862ns;
RA Shimada N., Maeda M., Urushihara H., Kawata T.;
RT "Identification of new modes of Dd-STATa regulation of gene expression in
RT Dictyostelium by in situ hybridisation.";
RL Int. J. Dev. Biol. 48:679-682(2004).
RN [5]
RP DEVELOPMENTAL STAGE [LARGE SCALE ANALYSIS].
RX PubMed=16386729; DOI=10.1016/j.ydbio.2005.11.035;
RA Iranfar N., Fuller D., Loomis W.F.;
RT "Transcriptional regulation of post-aggregation genes in Dictyostelium by a
RT feed-forward loop involving GBF and LagC.";
RL Dev. Biol. 290:460-469(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- DEVELOPMENTAL STAGE: Expressed in prestalk pstA and pstO cells in the
CC slug stage. Preferentially restricted to pstO cells during culmination.
CC Expression in the prestalk cells is reduced in dmtA-null cells.
CC Expression is gbfA-dependent. {ECO:0000269|PubMed:12796308,
CC ECO:0000269|PubMed:15470253, ECO:0000269|PubMed:16386729}.
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DR EMBL; AAFI02000055; EAL65738.1; -; Genomic_DNA.
DR RefSeq; XP_639057.1; XM_633965.1.
DR AlphaFoldDB; Q54R34; -.
DR STRING; 44689.DDB0229998; -.
DR PaxDb; Q54R34; -.
DR EnsemblProtists; EAL65738; EAL65738; DDB_G0283507.
DR GeneID; 8624082; -.
DR KEGG; ddi:DDB_G0283507; -.
DR dictyBase; DDB_G0283507; -.
DR HOGENOM; CLU_210588_0_0_1; -.
DR PRO; PR:Q54R34; -.
DR Proteomes; UP000002195; Chromosome 4.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..57
FT /note="Uncharacterized protein DDB_G0283507"
FT /id="PRO_0000392661"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 57 AA; 5763 MW; 9AC2CA23CE7AEECD CRC64;
MLFKSLQSIT SVNSIQKNQI SSISVGSSQA NNNAALLDAA ALVVIPGLLT AAAVAHI