ID   Y3508_METJA             Reviewed;         520 AA.
AC   Q60270;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Probable helicase MJECL08 {ECO:0000305};
DE            EC=3.6.4.12 {ECO:0000250|UniProtKB:F2Z5Z6};
GN   OrderedLocusNames=MJECL08 {ECO:0000312|EMBL:AAC37081.1};
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OG   Plasmid large ECE.
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC         Evidence={ECO:0000250|UniProtKB:F2Z5Z6};
CC   -!- SIMILARITY: Belongs to the HerA family. {ECO:0000305}.
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DR   EMBL; L77118; AAC37081.1; -; Genomic_DNA.
DR   PIR; H64510; H64510.
DR   RefSeq; WP_010890055.1; NC_001732.1.
DR   STRING; 243232.MJ_ECL08; -.
DR   EnsemblBacteria; AAC37081; AAC37081; MJ_ECL08.
DR   GeneID; 1450794; -.
DR   KEGG; mja:MJ_ECL08; -.
DR   eggNOG; arCOG00280; Archaea.
DR   HOGENOM; CLU_023842_2_0_2; -.
DR   InParanoid; Q60270; -.
DR   OMA; WINRIAK; -.
DR   OrthoDB; 33242at2157; -.
DR   PhylomeDB; Q60270; -.
DR   Proteomes; UP000000805; Plasmid large ECE.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR008571; HerA-like.
DR   InterPro; IPR018538; HerA_barrel_dom.
DR   InterPro; IPR033186; HerA_C.
DR   InterPro; IPR002789; HerA_central.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR42957; PTHR42957; 1.
DR   Pfam; PF05872; DUF853; 1.
DR   Pfam; PF01935; DUF87; 1.
DR   Pfam; PF09378; HAS-barrel; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Plasmid;
KW   Reference proteome.
FT   CHAIN           1..520
FT                   /note="Probable helicase MJECL08"
FT                   /id="PRO_0000107500"
FT   BINDING         162
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:Q97WG8"
FT   BINDING         171..176
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:Q97WG8"
FT   BINDING         501..502
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250|UniProtKB:Q97WG8"
SQ   SEQUENCE   520 AA;  58182 MW;  D1888AFDFE1D9079 CRC64;
     MMVINSVVVG TVVASKNVNE FEFVIENQVI DKIKKGEFVI TKNTHGDYLL SKITKIVSVN
     ALIGDKSEDA SELAKIRGVI YSEEMLNNSS KFLASAKILG VINNESGSIE SNVYPINVPQ
     NVYLTKDDLL AKIFSNGSIE VGYLKVRSST KVKLNAKELC SRHFAVLAMT GAGKSNTIAV
     LVQELFEKDK GKMNIVIVDP HGEYVKMRNT HILPAKLNPI LVPEEHLAKL LGIGENSSVQ
     KSFLVYAALT VKYECKENKK QISGLEYLKK IEEKLVECAD KIANSEDKKR IYIEYYDGTR
     CRXKTVKKDD EMSINRVIEK LRWFINKNKN ILGENEGMFD IKSDKINVLP LQKIEDEEAI
     TIVGEFLKRV LKERIKSVHD EIVEIKALEK PTLVIIEEAH LFAAKNLKDR SGYWINRIAK
     EGRKFGVGLG LVSQRPKELN PTVLSQMNTK IILRIVEPTD QKYILESSEN VGEDLLQDLP
     QLSTGEAIVV GSSLPLPALV KIKKYDGVLG GEDGLKNLKI