ID   Y3520_MYCTU             Reviewed;         347 AA.
AC   O53565; L0TED4;
DT   22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Putative coenzyme F420-dependent oxidoreductase Rv3520c;
DE            EC=1.-.-.-;
GN   OrderedLocusNames=Rv3520c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
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DR   EMBL; AL123456; CCP46342.1; -; Genomic_DNA.
DR   PIR; B70808; B70808.
DR   RefSeq; NP_218037.1; NC_000962.3.
DR   RefSeq; WP_003900084.1; NC_000962.3.
DR   AlphaFoldDB; O53565; -.
DR   SMR; O53565; -.
DR   STRING; 83332.Rv3520c; -.
DR   PaxDb; O53565; -.
DR   GeneID; 887310; -.
DR   KEGG; mtu:Rv3520c; -.
DR   PATRIC; fig|83332.111.peg.3921; -.
DR   TubercuList; Rv3520c; -.
DR   eggNOG; COG2141; Bacteria.
DR   InParanoid; O53565; -.
DR   OMA; FYIGGMG; -.
DR   PhylomeDB; O53565; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0009274; C:peptidoglycan-based cell wall; HDA:MTBBASE.
DR   GO; GO:0005886; C:plasma membrane; HDA:MTBBASE.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   Gene3D; 3.20.20.30; -; 1.
DR   InterPro; IPR019951; F420_OxRdatse_Rv3520c_pred.
DR   InterPro; IPR011251; Luciferase-like_dom.
DR   InterPro; IPR036661; Luciferase-like_sf.
DR   Pfam; PF00296; Bac_luciferase; 1.
DR   SUPFAM; SSF51679; SSF51679; 1.
DR   TIGRFAMs; TIGR03559; F420_Rv3520c; 1.
PE   1: Evidence at protein level;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..347
FT                   /note="Putative coenzyme F420-dependent oxidoreductase
FT                   Rv3520c"
FT                   /id="PRO_0000415512"
SQ   SEQUENCE   347 AA;  37617 MW;  FC693E217F2DE523 CRC64;
     MEAGMKLGLQ LGYWGAQPPQ NHAELVAAAE DAGFDTVFTA EAWGSDAYTP LAWWGSSTQR
     VRLGTSVIQL SARTPTACAM AALTLDHLSG GRHILGLGVS GPQVVEGWYG QRFPKPLART
     REYIDIVRQV WARESPVTSA GPHYRLPLTG EGTTGLGKAL KPITHPLRAD IPIMLGAEGP
     KNVALAAEIC DGWLPIFYSP RMAGMYNEWL DEGFARPGAR RSREDFEICA TAQVVITDDR
     AAAFAGIKPF LALYMGGMGA EETNFHADVY RRMGYTQVVD EVTKLFRSGR KDEAAEIIPD
     ELVDDAVIVG DIDHVRKQMA VWEAAGVTMM VVTAGSAEQV RDLAALV