ID   Y355_BACHK              Reviewed;         579 AA.
AC   Q6HP15;
DT   18-MAY-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=Probable methyl-accepting chemotaxis protein BT9727_0355;
GN   OrderedLocusNames=BT9727_0355;
OS   Bacillus thuringiensis subsp. konkukian (strain 97-27).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=281309;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=97-27;
RX   PubMed=16621833; DOI=10.1128/jb.188.9.3382-3390.2006;
RA   Han C.S., Xie G., Challacombe J.F., Altherr M.R., Bhotika S.S., Bruce D.,
RA   Campbell C.S., Campbell M.L., Chen J., Chertkov O., Cleland C.,
RA   Dimitrijevic M., Doggett N.A., Fawcett J.J., Glavina T., Goodwin L.A.,
RA   Hill K.K., Hitchcock P., Jackson P.J., Keim P., Kewalramani A.R.,
RA   Longmire J., Lucas S., Malfatti S., McMurry K., Meincke L.J., Misra M.,
RA   Moseman B.L., Mundt M., Munk A.C., Okinaka R.T., Parson-Quintana B.,
RA   Reilly L.P., Richardson P., Robinson D.L., Rubin E., Saunders E., Tapia R.,
RA   Tesmer J.G., Thayer N., Thompson L.S., Tice H., Ticknor L.O., Wills P.L.,
RA   Brettin T.S., Gilna P.;
RT   "Pathogenomic sequence analysis of Bacillus cereus and Bacillus
RT   thuringiensis isolates closely related to Bacillus anthracis.";
RL   J. Bacteriol. 188:3382-3390(2006).
CC   -!- FUNCTION: Chemotactic-signal transducers respond to changes in the
CC       concentration of attractants and repellents in the environment,
CC       transduce a signal from the outside to the inside of the cell, and
CC       facilitate sensory adaptation through the variation of the level of
CC       methylation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC       family. {ECO:0000305}.
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DR   EMBL; AE017355; AAT61241.1; -; Genomic_DNA.
DR   RefSeq; WP_000761099.1; NC_005957.1.
DR   RefSeq; YP_034705.1; NC_005957.1.
DR   AlphaFoldDB; Q6HP15; -.
DR   SMR; Q6HP15; -.
DR   EnsemblBacteria; AAT61241; AAT61241; BT9727_0355.
DR   KEGG; btk:BT9727_0355; -.
DR   PATRIC; fig|281309.8.peg.377; -.
DR   HOGENOM; CLU_000445_107_19_9; -.
DR   OMA; QEHVENA; -.
DR   Proteomes; UP000001301; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR   InterPro; IPR004090; Chemotax_Me-accpt_rcpt.
DR   InterPro; IPR003660; HAMP_dom.
DR   InterPro; IPR004089; MCPsignal_dom.
DR   Pfam; PF00672; HAMP; 1.
DR   Pfam; PF00015; MCPsignal; 1.
DR   PRINTS; PR00260; CHEMTRNSDUCR.
DR   SMART; SM00304; HAMP; 3.
DR   SMART; SM00283; MA; 1.
DR   PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR   PROSITE; PS50885; HAMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Chemotaxis; Membrane; Methylation; Transducer;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..579
FT                   /note="Probable methyl-accepting chemotaxis protein
FT                   BT9727_0355"
FT                   /id="PRO_0000394196"
FT   TOPO_DOM        1..13
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        14..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        35..198
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..579
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          223..274
FT                   /note="HAMP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00102"
FT   DOMAIN          293..529
FT                   /note="Methyl-accepting transducer"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00284"
FT   MOD_RES         289
FT                   /note="Glutamate methyl ester (Glu)"
FT                   /evidence="ECO:0000250"
FT   MOD_RES         548
FT                   /note="Glutamate methyl ester (Glu)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   579 AA;  64172 MW;  3E756CA69DBABBC7 CRC64;
     MKKYWHKLSF LQKNVLLTVL VILTLVGTMG ALSFNMFQNS MMSIFERHSF ETGDTVLHKL
     DEEIVRDVTK DPVAQREKRE KLTEKLDEAT EELNSVGQTY IVGAKKNEKG ELLIVDLSTD
     LANVVEVRPG EYYKQPDLWM EAYDKVMSTK KANMTVVYED LLGTWVTILE PIKDGEGNIV
     AIVAADVDAS IVPSTKEKFI IQGLMFICIS VLIATVIQFL IVRNALAPLR DLREGLRRVG
     EGDLNIKLEE RSDDIGIINS YFNNTIEKFK GIIDKVKQTA EQVSSSSQEL SVSTKENSMA
     VQEIVSSMVE LRAGAQLQET SVPQYLGIVY EVEDKMEEIT NAAKQMEKVS EGIEHHSVKG
     NGVTKQAINQ MNIIQNAVQD LSSIIYSLEV RSKEISDIVT VITSISNQTN SLALHATIEA
     SRAEETGEGF AVVADEVRKL AEQMEASAKD IANLIGETQA GTEEAVVSIR KASKEVESGM
     KLVEMNGAFF EEISKSAQSV TNQVRVVSSN SSDILQNSQN IVRVVNELSL IANTYTNSSS
     NVEESMKEQE MSVQDIAELA SSLSWLSQEL QELIGEFKS