ID   Y355_MYCPN              Reviewed;         242 AA.
AC   P75424;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Uncharacterized tRNA/rRNA methyltransferase MG252 homolog;
DE            EC=2.1.1.-;
GN   OrderedLocusNames=MPN_355; ORFNames=H91_orf242a, MP481;
OS   Mycoplasma pneumoniae (strain ATCC 29342 / M129) (Mycoplasmoides
OS   pneumoniae).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=272634;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29342 / M129;
RX   PubMed=8948633; DOI=10.1093/nar/24.22.4420;
RA   Himmelreich R., Hilbert H., Plagens H., Pirkl E., Li B.-C., Herrmann R.;
RT   "Complete sequence analysis of the genome of the bacterium Mycoplasma
RT   pneumoniae.";
RL   Nucleic Acids Res. 24:4420-4449(1996).
CC   -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC       superfamily. RNA methyltransferase TrmH family. {ECO:0000305}.
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DR   EMBL; U00089; AAB96129.1; -; Genomic_DNA.
DR   PIR; S73807; S73807.
DR   RefSeq; NP_110043.1; NC_000912.1.
DR   RefSeq; WP_010874711.1; NC_000912.1.
DR   AlphaFoldDB; P75424; -.
DR   SMR; P75424; -.
DR   STRING; 272634.MPN_355; -.
DR   EnsemblBacteria; AAB96129; AAB96129; MPN_355.
DR   KEGG; mpn:MPN_355; -.
DR   PATRIC; fig|272634.6.peg.382; -.
DR   HOGENOM; CLU_021322_0_1_14; -.
DR   OMA; QVPPYEY; -.
DR   BioCyc; MPNE272634:G1GJ3-558-MON; -.
DR   Proteomes; UP000000808; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR   GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   Gene3D; 3.40.1280.10; -; 1.
DR   InterPro; IPR029028; Alpha/beta_knot_MTases.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR   InterPro; IPR001537; SpoU_MeTrfase.
DR   InterPro; IPR013123; SpoU_subst-bd.
DR   InterPro; IPR029026; tRNA_m1G_MTases_N.
DR   PANTHER; PTHR46429; PTHR46429; 1.
DR   Pfam; PF00588; SpoU_methylase; 1.
DR   Pfam; PF08032; SpoU_sub_bind; 1.
DR   SMART; SM00967; SpoU_sub_bind; 1.
DR   SUPFAM; SSF55315; SSF55315; 1.
DR   SUPFAM; SSF75217; SSF75217; 1.
DR   TIGRFAMs; TIGR00186; rRNA_methyl_3; 1.
PE   3: Inferred from homology;
KW   Methyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..242
FT                   /note="Uncharacterized tRNA/rRNA methyltransferase MG252
FT                   homolog"
FT                   /id="PRO_0000159834"
FT   BINDING         198
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         218
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
FT   BINDING         227
FT                   /ligand="S-adenosyl-L-methionine"
FT                   /ligand_id="ChEBI:CHEBI:59789"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   242 AA;  27775 MW;  C117F83D8B6AA7A0 CRC64;
     MKRMQETSFL FGSKAFLEAL DNQLQIKKVN LSDKHQKLLG LIKKRGLRYE MHSSQWFHQQ
     FRHINHQEFV CVINPNQMLK TIEQLIQITD SKSTSTLVML HEIQDPHNFG AILRTCMAAE
     VDGIIFKKHN QAPINSTVIR TSMGTVFYQN LVQVTNLSYA ITTLQKHGFW TVATTLDERL
     KPKDYRQVDF DKRILLVGNE DKGLNALLLK NADLKVKIPM NPKLNSLNVS VAVGIILFGW
     KS